Personal profile
Research interests
My laboratory has been focused on the role of T cells in autoimmunity and transplantation. To this end, we have used a murine model, the parent-into-F1 model of graft-vs.-host disease to dissect the mechanisms, cellular immunology, cytokines and more recently the genes involved in the generation of acute cytotoxic GVHD vs. chronic lupus-like GVHD.
Keywords
- RB Pathology
- immunology
- Graft vs host disease
- lupus
- T cells
- QR180 Immunology
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Collaborations and top research areas from the last five years
Projects
- 7 Finished
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Mapping the genes that predispose to murine lupus
Via, C. (PI)
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
1/02/20 → 31/01/23
Project: Research
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Antibody-based prophylactic EBV vaccine
Via, C. (PI) & Snapper, C. M. (CoPI)
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
27/04/16 → 31/03/20
Project: Research
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Immunopathogenesis of Lupus
Via, C. (PI)
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
1/08/14 → 31/07/16
Project: Research
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Immunopathogenesis of Lupus
Via, C. S. (PI) & Via, C. (CoPI)
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
1/02/01 → 31/07/14
Project: Research
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CENTER FOR ALTERNATIVE MEDICINE RESEARCH OF ARTHRITIS
Berman, B. M. (PI), Via, C. (CoPI), Ezzo, J. J. M. (CoPI), Lao, L. L. N. (CoPI), Hochberg, M. M. C. (CoPI) & Stewart, W. F. (CoPI)
30/09/99 → 31/07/06
Project: Research
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Sex differences in donor T cell targeting of host splenocyte subpopulations in acute and chronic murine graft-vs-host disease: results from a novel induction and assessment protocol with implications for lupus-like autoimmunity
Soloviova, K. & Via, C. S., 1 Oct 2025, In: ImmunoHorizons. 9, 10, vlaf039.Research output: Contribution to journal › Article › peer-review
Open Access -
Hybrid cytokine IL233 renders protection in murine acute graft vs host disease (aGVHD)
Venkatadri, R., Sabapathy, V., Dogan, M., Sharma, R., Mohammad, S., Via, C. S. & Sharma, R., Jun 2021, In: Cellular Immunology. 364, p. 104345 1 p., 104345.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
B cell depletion in murine lupus using cytotoxic T lymphocytes in vivo: Feasibility and benefit: Feasibility and benefit
Soloviova, K., Puliaeva, I., Puliaiev, M., Puliaev, R. & Via, C. S., Jul 2020, In: Cellular Immunology. 353, 1 p., 104117.Research output: Contribution to journal › Article › peer-review
Open Access -
Both perforin and FasL are required for optimal CD8 T cell control of autoreactive B cells and autoantibody production in parent-into-F1 lupus mice
Soloviova, K., Puliaiev, M., Puliaev, R., Puliaeva, I. & Via, C. S., Sep 2018, In: Clinical Immunology. 194, p. 34-42 9 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
In vivo IL-4 prevents allo-antigen driven CD8+ CTL development
Via, C. S., Soloviova, K., Puliaiev, M., Puliav, R., Puliaeva, I., Morris, S. C. & Finkelman, F. D., 1 Jul 2017, In: Clinical Immunology. 180, p. 11-24 14 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations