immunologic tolerance, hemophilia, autoimmunity

My lab is focussed on translational immunology targeting adverse immune respnoses to used gen therpy to achieve immunologic tolerance in hemophilia, autoimmunity

David W. Scott, Ph.D. is Vice Chair for Research in the Department of Medicine at the Uniformed Services School of Health Sciences (USUHS) in Bethesda, MD. An alumnus of Antioch College, Dr. Scott received his M.S. degree from the University of Chicago and Ph.D. from Yale University in 1969. Following a post-doctoral fellowship at Oxford University, UK, he joined the faculty at Duke University in 1971, where he initiated his National Institute of Health-funded studies on immune tolerance mechanisms. In 1983, he was named Dean's Professor of Immunology at the University of Rochester, a post he held for 11 winters. Dr. Scott thereafter became Head of the newly formed Immunology Department at the Holland Lab of the American Red Cross, and moved to the University of Maryland School of Medicine in 2004. He assumed his current position at USUHS in September 2010.
Dr. Scott has contributed to over 200 research papers on several subjects in immunology, focusing on immunologic tolerance, gene therapy, and most recently on engineering regulatory T cells for application in autoimmune diseases and hemophilia. He is the author of two textbooks, including a monograph entitled, The Nature of Immunologic Tolerance, and recipient of a number of awards, including the Distinguished Service Award from the American Association of Immunologists (AAI, 2004), a Boerhaave Professorship at Leiden University Medical School, The Netherlands (2006) and the 2009 Scientific Achievement Award from the American Association of Pharmaceutical Scientists.
Active in science education, Dr. Scott has been Chair of Education Committees at the American Society for Microbiology and AAI. He has also served on the editorial boards of major immunologic journals, and as a member of National Multiple Sclerosis Society, Juvenile Diabetes Research Foundation and NIH Study Sections.