Research output per year
Research output per year
Personal profile
Biography
Dr. Regules (COL MC USA) is an infectious diseases physician and research leader for the US Army. His research encompasses clinical trials, malaria , biodefense, product development, international research, and vaccinology. Dr. Regules is currently the Director for the Foundational Sciences Directorate at the United States Army Medical Research Institute of Infectious Diseases (USAMRIID), an Associate Professor of Medicine at the USUHS, and affiliated staff at the Walter Reed National Military Medical Center. He is a Fellow of both the Infectious Diseases Society of America and the American College of Physicians.
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Collaborations and top research areas from the last five years
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A candidate antibody drug for prevention of malaria
Williams, K. L., Guerrero, S., Flores-Garcia, Y., Kim, D., Williamson, K. S., Siska, C., Smidt, P., Jepson, S. Z., Li, K., Dennison, S. M., Mathis-Torres, S., Chen, X., Wille-Reece, U., MacGill, R. S., Walker, M., Jongert, E., King, C. R., Ockenhouse, C., Glanville, J., Moon, J. E., & 10 others, Jan 2024, In: Nature Medicine. 30, 1, p. 117-129 13 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Recombinant Full-length Plasmodium falciparum Circumsporozoite Protein–Based Vaccine Adjuvanted With Glucopyranosyl Lipid A–Liposome Quillaja saponaria 21: Results of Phase 1 Testing With Malaria Challenge
Friedman-Klabanoff, D. A. J., Berry, A. A., Travassos, M. A., Shriver, M., Cox, C., Butts, J., Lundeen, J. S., Strauss, K. A., Joshi, S., Shrestha, B., Mo, A. X., Nomicos, E. Y. H., Deye, G. A., Regules, J. A., Bergmann-Leitner, E. S., Pasetti, M. F. & Laurens, M. B., 15 Jun 2024, In: Journal of Infectious Diseases. 229, 6, p. 1883-1893 11 p.Research output: Contribution to journal › Article › peer-review
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SARS-CoV-2 recombinant spike ferritin nanoparticle vaccine adjuvanted with Army Liposome Formulation containing monophosphoryl lipid A and QS-21: a phase 1, randomised, double-blind, placebo-controlled, first-in-human clinical trial
EID-030 Study Group, Jun 2024, In: The Lancet Microbe. 5, 6, p. e581-e593Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Late-presenting Plasmodium falciparum Malaria in a Non-Endemic Setting During COVID-19 Travel Restrictions
Robben, P. M., Dunbar, C. R., Akin, E. H., Pichugin, A. & Regules, J. A., 1 May 2023, In: Military Medicine. 188, 5-6, p. e1335-e1337Research output: Contribution to journal › Article › peer-review
Open Access -
Novel antibody competition binding assay identifies distinct serological profiles associated with protection
Bolton, J. S., MacGill, R. S., Locke, E., Regules, J. A. & Bergmann-Leitner, E. S., 2023, In: Frontiers in Immunology. 14, 1303446.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations
Press/Media
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Study Findings from Walter Reed Army Institute of Research Provide New Insights into Liposomes [Unglycosylated Soluble SARS-CoV-2 Receptor Binding Domain (RBD) Produced in E. coli Combined with the Army Liposomal Formulation Containing ...]
Nelson L. Michael & Jason A. Regules
2/02/23
1 item of Media coverage
Press/Media
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Malaria vaccine candidate safe and immunogenic following first-in-human trials
14/09/22
2 items of Media coverage
Press/Media
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Malaria vaccine candidate safe and immunogenic following first-in-human trials
14/09/22
2 items of Media coverage
Press/Media
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First-Ever Malaria Vaccine Has Roots in Army Medical Research
22/10/21
1 item of Media coverage
Press/Media