Personal profile
Biography
Dr. Rouse, Research Assistant Professor in the Department of Surgery, joined USU in August 2021. Dr. Rouse has spent over 20 years in the areas of drug discovery, preclinical pipeline development, product advancement, host immunology, immunotherapy, bacteria-host interactions, and wound healing and care. Throughout his career, he has been awarded over $14M collectively in research funding to help address a broad range of technical and knowledge gaps within the biomedical field.
Dr. Rouse routinely leads and manages interdisciplinary and cross-functional teams across a broad range of scientific areas, such as microbiology, immunology, biomaterial engineering, biophysics, and computational biology, to promote product development and maximize clinical outcomes requiring complex medical decision making. In addition to his appointment as a USUHS Research Assistant Professor under the Department of Surgery, Dr. Rouse currently works as the Lead Scientist for Surgical Critical Care Initiative (SC2i) and the Walter Reed National Military Medical Center (WRNMMC). His laboratory routinely collaborates and uses multi-omics (proteins, transcripts, genomics) approaches to manage and facilitate the development of biomarker-driven Clinical Decision Support Tools (CDSTs), such as advanced analytics, machine learning, and precision medicine diagnostics. Dr. Rouse is primarily focused on identifying biomarkers and developing new assays to better understand the translational mechanisms and improve clinical outcomes of combat-related injuries and conditions.
Education/Academic qualification
Biomedical Sciences (Immunology), PhD, University of South Carolina
Award Date: 20 Dec 2023
Biological Sciences, Master, University of Virginia
Award Date: 20 May 2023
Biochemistry, Bachelor, University of Maryland Baltimore County
Award Date: 20 Mar 2023
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Collaborations and top research areas from the last five years
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Exploratory cluster analysis of IL2Ra and associated biomarkers and complications after blunt chest trauma
Haines, K. L., Li, R., Grey, S., Kim, H. E., Gann, E., Almond, C., Rouse, M., Joshi, M. B., Schobel-McHugh, S., Agarwal, S., Kirk, A., Elster, E. & Fernandez-Moure, J. S., Jun 2025, In: Journal of Trauma and Acute Care Surgery. 98, 6, p. 899-906 8 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Seraph-100 hemoperfusion for management of severe COVID-19: Assessment of serum and plasma analytes pre- and post-filtration
Rouse, M., Gann, E. R., Brandsma, J., Sugiharto, V. A., Robertson, H., Genzor, P., Chen, H-W., Simons, M. P., Schobel, S. A., Chenoweth, J. G., Jenkins, S. A., Clark, D. V., Della Volpe, J., Chitty, S., Rivera, I. M., Lewis, M., Park, C., Parikh, A., Vir, P., Stewart, I. J., & 1 others, 11 Dec 2024, (E-pub ahead of print) In: Blood Purification. p. 1-16 16 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
The influence of microbial colonization on inflammatory versus pro-healing trajectories in combat extremity wounds
Schobel, S. A., Gann, E. R., Unselt, D., Grey, S. F., Lisboa, F. A., Upadhyay, M. M., Rouse, M., Tallowin, S., Be, N. A., Zhang, X., Dalgard, C. L., Wilkerson, M. D., Hauskrecht, M., Badylak, S. F., Zamora, R., Vodovotz, Y., Potter, B. K., Davis, T. A. & Elster, E. A., 4 Mar 2024, In: Scientific Reports. 14, 1, p. 5006 5006.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Host CD3+ T-cells can significantly modulate phage treatment effects on bacterial bioburden in mouse models
Li, R., Rouse, M., Pace, B. T., Grey, S. F., Mclaughlin, K., Schobel, S. A. & Simons, M. P., 2023, In: Frontiers in Microbiology. 14, p. 1240176 1240176.Research output: Contribution to journal › Article › peer-review
Open Access -
Blast Waves Cause Immune System Dysfunction and Transient Bone Marrow Failure in a Mouse Model
Bergmann-Leitner, E. S., Bobrov, A. G., Bolton, J. S., Rouse, M. D., Heyburn, L., Pavlovic, R., Garry, B. I., Alamneh, Y., Long, J., Swierczewski, B., Tyner, S., Getnet, D., Sajja, V. S. & Antonic, V., 22 Mar 2022, In: Frontiers in Bioengineering and Biotechnology. 10, 821169.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations
Press/Media
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WOUNDX™: REVOLUTIONIZING WOUND CARE TO IMPROVE WARFIGHTER READINESS AND REDUCE COSTS
Henry Robertson, Felipe Lisboa, Michael Rouse, Eric Elster, Scott Grey & Seth Schobel-McHugh
23/04/25
2 items of Media coverage
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Study Results from Uniformed Services University of the Health Sciences Broaden Understanding of COVID-19 (Seraph 100 Hemoperfusion for Management of Severe Covid-19: Assessment of Serum and Plasma Analytes Pre- and Post-filtration)
Ian Stewart, Henry Robertson, Eric Gann, Mark Simons, Kathleen Pratt, Seth Schobel-McHugh & Michael Rouse
4/03/25
1 item of Media coverage
Press/Media
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Uniformed Services University of the Health Sciences Researchers Provide New Study Findings on Genetics (The influence of microbial colonization on inflammatory versus pro-healing trajectories in combat extremity wounds)
Clifton Dalgard, Eric Gann, Thomas Davis, Matthew Wilkerson, Benjamin K Potter, Eric Elster, Seth Schobel-McHugh, Simon Tallowin, Scott Grey, Michael Rouse & Felipe Lisboa
18/03/24
1 item of Media coverage
Press/Media
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Uniformed Services University of the Health Sciences Researchers Describe Findings in Microbiology (Host CD3+ T-cells can significantly modulate phage treatment effects on bacterial bioburden in mouse models)
Mark Simons, Seth Schobel-McHugh, Kimberly McLaughlin,, Scott Grey & Michael Rouse
25/09/23
1 item of Media coverage
Press/Media