Projects per year
Personal profile
Biography
I am currently the Associate Director of the Gynecologic Cancer Center of Excellence and an Assistant Professor in the Department of Gynecologic Surgery and Obstetrics at Uniformed Services University of the Health Sciences. My training has been focused on basic cell and molecular cancer research as well as application and development of analytical mass spectrometry-based proteomics and bioinformatic approaches to support multi-omic analyses of human tissues and proximal biofluids. I have applied this training throughout my scientific career to basic, translational, and clinical research investigations focused on defining relationships between the human proteome, genome and disease. My current research is focused on refining sample preparation and informatics strategies to support multi-omic analyses of human tissues that leverages cutting-edge histopathologic techniques such as laser microdissection microscopy with an emphasis on defining molecular drivers underlying disease etiology and progression, multidrug resistance and racial disparities in gynecologic malignancies. My personal scientific goal is to leverage high-throughput proteomics and orthogonal multi-omic approaches to define mechanistic biology that is central to disease pathogenesis and translate these findings to the clinic as refined diagnostic methods and therapeutic approaches that will empower personalized medicine and improve the clinical management of cancer and human disease as a whole.
Education/Academic qualification
Postdoctoral Fellowship in Cell Biology and Molecular Physiology, University of Pittsburgh School of Medicine
2010 → 2012
Molecular Pharmacology, PhD, University of Pittsburgh
2006 → 2010
Biological Sciences, Bachelor, University at Buffalo
1997 → 2010
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Collaborations and top research areas from the last five years
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Author Correction: Proteogenomic analysis of enriched HGSOC tumor epithelium identifies prognostic signatures and therapeutic vulnerabilities (npj Precision Oncology, (2024), 8, 1, (68), 10.1038/s41698-024-00519-8)
The APOLLO Research Network, Dec 2024, In: npj Precision Oncology. 8, 1, 97.Research output: Contribution to journal › Comment/debate
Open Access -
Disease progression, survival, and molecular disparities in Black and White patients with endometrioid endometrial carcinoma in real-world registries and GOG/NRG oncology randomized phase III clinical trials
Kopelman, Z. A., Tian, C., Tumas, J., Phippen, N. T., Tarney, C. M., Hope, E. R., Winkler, S. S., Jokajtys, S., Kucera, C. W., Chan, J. K., Richardson, M. T., Kapp, D. S., Hamilton, C. A., Leath, C. A., Jones, N. L., Rocconi, R. P., Farley, J. H., Secord, A. A., Cosgrove, C. M., Powell, M. A., & 7 others , Apr 2024, In: Gynecologic Oncology. 183, p. 103-114 12 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Immuno-Molecular Targeted Therapy Use and Survival Benefit in Patients with Stage IVB Cervical Carcinoma in Commission on Cancer®-Accredited Facilities in the United States
Sitler, C. A., Tian, C., Hamilton, C. A., Richardson, M. T., Chan, J. K., Kapp, D. S., Leath, C. A., Casablanca, Y., Washington, C., Chappell, N. P., Klopp, A. H., Shriver, C. D., Tarney, C. M., Bateman, N. W., Conrads, T. P., Maxwell, G. L., Phippen, N. T. & Darcy, K. M., Mar 2024, In: Cancers. 16, 5, 1071.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Mapping three-dimensional intratumor proteomic heterogeneity in uterine serous carcinoma by multiregion microsampling
Hunt, A. L., Bateman, N. W., Barakat, W., Makohon-Moore, S. C., Abulez, T., Driscoll, J. A., Schaaf, J. P., Hood, B. L., Conrads, K. A., Zhou, M., Calvert, V., Pierobon, M., Loffredo, J., Wilson, K. N., Litzi, T. J., Teng, P. N., Oliver, J., Mitchell, D., Gist, G., Rojas, C., & 7 others , Dec 2024, In: Clinical Proteomics. 21, 1, 4.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Microenvironment shapes small-cell lung cancer neuroendocrine states and presents therapeutic opportunities
Desai, P., Takahashi, N., Kumar, R., Nichols, S., Malin, J., Hunt, A., Schultz, C., Cao, Y., Tillo, D., Nousome, D., Chauhan, L., Sciuto, L., Jordan, K., Rajapakse, V., Tandon, M., Lissa, D., Zhang, Y., Kumar, S., Pongor, L., Singh, A., & 38 others , 18 Jun 2024, In: Cell Reports Medicine. 5, 6, 101610.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations
Press/Media
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Study Findings from Uniformed Services University of the Health Sciences Broaden Understanding of Leiomyomas (Multiomic Analysis of Uterine Leiomyomas In Self-described Black and White Women: Molecular Insights Into Health Disparities)
Clifton Dalgard, Nicholas Bateman, Matthew Wilkerson, Thomas Conrads, Kathleen Darcy & Larry Maxwell
8/10/24
1 item of Media coverage
Press/Media
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Researcher from Uniformed Services University of the Health Sciences Discusses Findings in Cancer (A modified dual preparatory method for improved isolation of nucleic acids from laser microdissected fresh-frozen human cancer tissue specimens)
Clifton Dalgard, Nicholas Bateman, Craig Shriver & Thomas Conrads
2/10/24
1 item of Media coverage
Press/Media
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Empowering Women's Health: Gynecologic Cancer Center of Excellence's 20-Year Journey of Innovation, Impact
Nicholas Bateman, Craig Shriver, Thomas Conrads, Kathleen Darcy & Larry Maxwell
24/05/24
1 item of Media coverage
Press/Media
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New Squamous Cell Carcinoma Findings from Uniformed Services University of the Health Sciences Described (Survival Disparities In Non-hispanic Black and White Cervical Cancer Patients Vary By Histology and Are Largely Explained By Modifiable ...)
Nicholas Bateman, Craig Shriver, Yovanni Casablanca, Thomas Conrads, Kathleen Darcy & Larry Maxwell
8/05/24
1 item of Media coverage
Press/Media
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New Precision Oncology Research from Uniformed Services University of the Health Sciences Described (Proteogenomic analysis of enriched HGSOC tumor epithelium identifies prognostic signatures and therapeutic vulnerabilities)
Clifton Dalgard, Nicholas Bateman, Matthew Wilkerson, Craig Shriver, Thomas Conrads, Kathleen Darcy & Jerry Lee
29/03/24
1 item of Media coverage
Press/Media