Personal profile
Biography
Dr. Seth Schobel is the Scientific Director for the SC2i and an Associate Professor in the Department of Surgery. He has a background in Cell Biology and Molecular Genetics and received his MS (Johns Hopkins University) and PhD (University of Maryland, College Park) in Bioinformatics, Computational Biology and Genomics. His research interests have centered around host-pathogen interactions, virology, immunology, systems biology, data science, machine learning, and biostatistics. Currently, he is working to better understand the molecular and regulatory underpinnings of wound healing and tissue regeneration as well as how microbial interactions influence the healing process. As Scientific Director of the SC2i he has been utilizing his skills in bioinformatics and data science to develop a cloud computing environment to enable big data interrogations of the aforementioned systems. Specifically, together with the SC2i, he is utilizing various Machine Learning approaches to further operationalize this data into Clinical Decisions Support Tools within real-world clinical workflows to increase the fidelity of clinical decisions.
Education/Academic qualification
Computational Biology, Bioinformatics, and Genomics, PhD, The Viral Genomics Revolution: Big Data Approaches to Basic Viral Research, Surveillance, and Vaccine Development., University of Maryland
30 Aug 2010 → 17 Aug 2015
Award Date: 17 Aug 2015
Bioinformatics, Master, Johns Hopkins University
1 Sep 2006 → 23 May 2009
Award Date: 23 May 2009
Cell Biology and Molecular Genetics, Bachelor, University of Maryland
25 Jan 1997 → 19 May 2001
Award Date: 19 May 2001
Art History and Archaeology, Bachelor, University of Maryland
25 Jan 1997 → 19 May 2001
Award Date: 19 May 2001
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Collaborations and top research areas from the last five years
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Continuous Physiologic Markers of Heart Rate Variability Derived From Bedside Electrocardiogram Precede Onset of Acute Respiratory Distress Syndrome: A Physiologic Modeling Study
Marshall, C. E., Shi, H., Ali, A., Moas, V., Davis, C. M., Wang, J., Narendrula, S., Vale, J. G. D. S., Song, J., Jeong, H., Krishnan, P., Gent, A., Tallowin, S., Lisboa, F. A., Schobel, S. A., Elster, E. A., Buchmann, T. G., Dente, C. J., Yang, P. & Kamaleswaran, R., 1 Dec 2025, In: Critical Care Explorations. 7, 12, p. e1352Research output: Contribution to journal › Article › peer-review
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Predicting Vasospasm and Early Mortality in Severe Traumatic Brain Injury: A Model Using Serum Cytokines, Neuronal Proteins, and Clinical Data
Rindler, R. S., Robertson, H., De Yampert, L. S., Khatri, V., Texakalidis, P., Eshraghi, S., Grey, S., Schobel, S., Elster, E. A., Boulis, N. & Grossberg, J. A., 1 May 2025, In: Neurosurgery. 96, 5, p. 1133-1145 13 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Derivation and Validation of Generalized Sepsis-induced Acute Respiratory Failure Phenotypes Among Critically Ill Patients: A Retrospective Study
Choudhary, T., Upadhyaya, P., Davis, C. M., Yang, P., Tallowin, S., Lisboa, F. A., Schobel, S. A., Coopersmith, C. M., Buchman, T. G., Dente, C. J., Kamaleswaran, R. & Elster, E., 30 Apr 2024, In: Research square. 28, 1, 321.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Predicting Sepsis Induced Hypotension Patient Attributes for Restrictive vs Liberal Fluid Strategy
Upadhyaya, P., Wang, J., Mathew, D. T., Ali, A., Tallowin, S., Gann, E., Lisboa, F. A., Schobel, S. A., Elster, E. A., Buchman, T. G., Dente, C. J. & Kamaleswaran, R., 2024, In: Shock. 2506.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Seraph-100 hemoperfusion for management of severe COVID-19: Assessment of serum and plasma analytes pre- and post-filtration
Rouse, M., Gann, E. R., Brandsma, J., Sugiharto, V. A., Robertson, H., Genzor, P., Chen, H-W., Simons, M. P., Schobel, S. A., Chenoweth, J. G., Jenkins, S. A., Clark, D. V., Della Volpe, J., Chitty, S., Rivera, I. M., Lewis, M., Park, C., Parikh, A., Vir, P., Stewart, I. J., & 1 others, 11 Dec 2024, (E-pub ahead of print) In: Blood Purification. p. 1-16 16 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations
Press/Media
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WOUNDX™: REVOLUTIONIZING WOUND CARE TO IMPROVE WARFIGHTER READINESS AND REDUCE COSTS
Henry Robertson, Felipe Lisboa, Michael Rouse, Eric Elster, Scott Grey & Seth Schobel-McHugh
23/04/25
2 items of Media coverage
Press/Media
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Study Results from Uniformed Services University of the Health Sciences Broaden Understanding of COVID-19 (Seraph 100 Hemoperfusion for Management of Severe Covid-19: Assessment of Serum and Plasma Analytes Pre- and Post-filtration)
Ian Stewart, Henry Robertson, Eric Gann, Mark Simons, Kathleen Pratt, Seth Schobel-McHugh & Michael Rouse
4/03/25
1 item of Media coverage
Press/Media