Personal profile
Biography
My research program explores the fundamental intersection of the hypothalamic-pituitary-gonadal (HPG) and hypothalamic-pituitary-adrenal (HPA) axes in shaping behavior and physiology. Grounded in my training as a reproductive neuroendocrinologist and neuroanatomist, I have established a research framework focused on uncovering the neural circuitry and molecular underpinnings governing both gonadotropin-releasing hormone regulation and the stress response. Specifically, my work investigates how sex hormones and traumatic insults—such as mild traumatic brain injury (TBI) and sleep restriction—interact to drive sex-dependent biological outcomes, neuroimmune dysregulation, and the development of stress-related disorders.
Education/Academic qualification
Physiology, PhD, Texas A&M University
Keywords
- QP Physiology
- Neuroendocrinology
- Stress
- Hormones
- Women's Health
- Traumatic Brain Injury
- Sleep
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Collaborations and top research areas from the last five years
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Neuroanatomical and behavioral characterization of corticotropin releasing factor-expressing lateral Habenula neurons in mice
Flerlage, W. J., Gouty, S. C., Thomas, E. H., Simmons, S. C., Tsuda, M. C., Rujan, O. L., Armstrong, R. C., Davis, C. M., Iyer, L., Petrus, E., Cox, B. M., Wu, T. J. & Nugent, F. S., 8 Apr 2026, In: bioRxiv : the preprint server for biology.Research output: Contribution to journal › Article › peer-review
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Molecular Mechanisms of Estrogen Receptors and their Relevance to Anxiety
Stewart, S., Acevedo-Rodriguez, A., Sharma, D., Zuloaga, D., Wu, T. J. & Mani, S., 2025, (Submitted) Brain Estrogen Receptors: Neuromethods Series. SpringerResearch output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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PTEN status on gonadotropin-releasing hormone (GnRH) metabolite, GnRH-(1–5), effects in endometrial cancer cell lines migration, & transcriptomic analysis of basal cell line and tumor gene expressions†
Cho-Clark, M., Sukumar, G., Raiciulescu, S., Dalgard, C., Mariño-Ramírez, L. & Wu, T. J., 1 Dec 2025, In: Biology of Reproduction. 113, 6, p. 1562-1575 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Chronically stressed male and female mice show a similar peripheral and central pro-inflammatory profile after an immune challenge
Careaga, M. & Wu, T. J., 2024, In: PLoS ONE. 19Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Editorial: The bidirectional relationship between sleep and neuroendocrinology
Suchecki, D., Wu, T. J. & Meerlo, P., 2024, In: Frontiers in Endocrinology.Research output: Contribution to journal › Comment/debate
1 Scopus citations
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Research from Uniformed Services University of the Health Sciences Reveals New Findings on Life Science (Neuroanatomical and behavioral characterization of corticotropin releasing factor-expressing lateral Habenula neurons in mice)
Davis-Takacs, C., Nugent, F., Armstrong, R., Petrus, E. & Wu, T. J.
12/05/26
1 item of Media coverage
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Investigators from Uniformed Services University of the Health Sciences Release New Data on Endometrial Cancer [Pten Status On Gonadotropin-releasing Hormone (Gnrh) Metabolite, Gnrh-(1-5), Effects In Endometrial Cancer Cell Lines Migration, & ...]
Raiciulescu, S., Dalgard, C. & Wu, T. J.
1/10/25
1 item of Media coverage
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WMMC Auxiliary awards Health Career Scholarships to six students
12/05/25
1 item of Media coverage
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