Projects per year
Personal profile
Research interests
Skin tumors
Biography
Thomas Darling, MD PhD, is Professor, Dermatology Division, Department of Medicine at the Uniformed Services University in Bethesda, MD. Tom received his MD and PhD degrees from Duke University. He completed medicine internship at UNC Hospitals, dermatology residency at Duke University, and a research fellowship in the Dermatology Branch, National Cancer Institute, NIH, before joining the faculty at USU in 1999. His laboratory studies hamartoma syndromes and skin regeneration. They were the first to demonstrate human hair follicle neogenesis in dermal epidermal composites. Ongoing studies are aimed at developing a next generation skin substitute that regenerates normal skin structures vital for function and appearance.
Education/Academic qualification
1979-1983 B.S. in Biology, Houghton College, Houghton, NY
1983-1990 M.D.-Ph.D., Duke University School of Medicine, Duke University Graduate School, Department of Cell Biology, Durham, NC,
1990-1991 Medicine Internship, UNC Hospitals, Chapel Hill, NC
1991-1994 Dermatology Residency, Duke University Medical Center, Durham, NC
1994-1996 Clinical Associate, Dermatology Branch, NIH, Bethesda, MD
1996-1998 Clinical Fellow, Dermatology Branch, NIH, Bethesda, MD
Keywords
- RL Dermatology
- Skin tumors
- Skin regeneration
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Collaborations and top research areas from the last five years
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Countermeasures for Radiation-Induced Dermatitis
Day, R. (PI), Darling, T. (CoI) & Pasieka, H. (CoI)
Uniformed Services University Program, Department of Defense CDMRP, RION, Inc.
29/08/20 → 31/07/27
Project: Research
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Regulation of Dermal Fibroblasts in Skin Regeneration and Healing
Darling, T. (PI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases
1/09/12 → 31/08/15
Project: Research
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Novel in vitro and xenograft models to study treatments for tuberous sclerosis
Darling, T. (PI)
1/07/06 → 30/06/09
Project: Research
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Clinical Characterization of Skin Findings on the Hands in Proteus Syndrome
Verling, S. D., Gaidici, N., Biesecker, L. G., Darling, T. N. & Ours, C. A., 2026, (Accepted/In press) In: Pediatric Dermatology.Research output: Contribution to journal › Article › peer-review
Open Access -
Murine Model of Radiation Dermatitis with Experimental Wound and Effects of Genistein
Phillips, E. O. N., Alzahrani, A., Rittase, W. B., Slaven, J. E., Aduba, D. C., Xavier, S., Wang, J. A., Hays, E. C., Craig, D., Streett, G. E., Sperling, L., Lee, S. H., Pasieka, H. B., Darling, T. N. & Day, R. M., 2 Jun 2026, In: International Journal of Molecular Sciences. 27, 11, 5019.Research output: Contribution to journal › Article › peer-review
Open Access -
A Matrix-Derived Bioactive Peptide Enhances Epidermal Thickness and Hair Follicle Neogenesis in Grafted Dermal–Epidermal Composites
Xavier, S., Roy, J., Li, S., Klover, P. J., Thangapazham, R. L., Wang, J. A., Aduba, D. C., Raiciulescu, S., Sperling, L. C., Herman, I. M. & Darling, T. N., Jan 2025, In: Wound Repair and Regeneration. 33, 3, p. e70036 e70036.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
A Novel Approach to Pattern Dermal Papilla Spheroids in Dermal–Epidermal Composites Using Non-Adherent Microwell Arrays
Wisdom, E. C., Aduba, D. C., Lewis, O., Xavier, S., Phillips, E. O. N., Gilchrist, K. H., Herman, I. M., Ho, V. B., Darling, T. N. & Klarmann, G. J., 21 Nov 2025, In: Bioengineering. 12, 12, p. 1281 1281.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
The Use of Therapeutic Peptides in Combination with Full-Thickness Skin Columns to Improve Healing of Excisional Wounds
Carlsson, A. H., Herman, I. M., Christy, S., Larson, D., Chan, R. K., Darling, T. N. & Nuutila, K., Aug 2025, In: Bioengineering. 12, 8, 856.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations
Press/Media
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USU Researchers Use Therapeutic Peptides to Develop Skin Substitutes for Wound Healing
18/06/25
1 Media contribution
Press/Media
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Leonard Sperling Receives Helwig Award From the American Society of Dermatopathology
2/02/24
1 item of Media coverage
Press/Media
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DR. LEONARD SPERLING RECEIVES HELWIG AWARD FROM THE AMERICAN SOCIETY OF DERMATOPATHOLOGY
1/02/24
2 items of Media coverage
Press/Media
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Dr. Leonard Sperling Receives Helwig Award from the American Society of Dermatopathology
1/02/24
1 item of Media coverage
Press/Media