CLINICAL IMPLICATIONS OF PHARMACOLOGIC ALTERATIONS OF THROMBOSIS FOLLOWING MEDERATE-TO-SEVERE AND PENETRATING TRAUMATIC BRAIN INJURY

  • Bell, Randy (PI)

Project Details

Description

Background: Venous thromboembolism, including deep vein thrombosis (DVT) and pulmonary embolism (PE), are common life-threatening complications of severe traumatic brain injury (TBI). Despite the potential for venous thromboembolism chemoprophylaxis treatment (VTC) to reduce the risk of these complications and improve outcomes, use of this treatment in patients with TBI remains controversial. Our previous study of military patients with severe TBI in Iraq and Afghanistan showed potential for benefit from use of VTC. However, a larger study is needed to confirm this conclusion.Objective/Hypotheses: In patients with severe closed and penetrating brain injury sustained in the wars in Iraq and Afghanistan, we hypothesize that early administration of VTC within

StatusFinished
Effective start/end date29/09/1728/09/20

Funding

  • Congressionally Directed Medical Research Programs: $648,792.00

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