A Clinical Approach to Rhabdomyolysis

Nicol Voermans; Salman Bhai; Nick Kruijt; Felix Kleefeld; Mads Godtfeldt Stemmerik; Gina Ravenscroft; Francis O'Connor; Pascal Laforet; John Vissing

doi:10.1016/B978-0-323-95702-1.00251-7

A Clinical Approach to Rhabdomyolysis

Nicol Voermans
, Salman Bhai
, Nick Kruijt
, Felix Kleefeld
, Mads Godtfeldt Stemmerik
, Gina Ravenscroft
, Francis O'Connor
, Pascal Laforet
, John Vissing

Military and Emergency Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Rhabdomyolysis is a medical emergency characterized by acute skeletal muscle breakdown with a sudden strong rise and subsequent fall of serum creatine kinase (CK) levels. Rhabdomyolysis events are provoked by exposure to external triggers, sometimes in combination with an increased genetic susceptibility. In this chapter, we will provide a summary on the etiology of exertional rhabdomyolysis and an overview of the triggers and genetic susceptibilities in adults with rhabdomyolysis, summarize the (sub) acute management of patients with exertional rhabdomyolysis, present a diagnostic approach to patients with exertional rhabdomyolysis, and provide recommendations for daily activities and sports after an episode of rhabdomyolysis to prevent a recurrent episode.

Original language	English
Title of host publication	Encyclopedia of the Neurological Sciences
Publisher	Elsevier
Pages	V4:448-V4:459
ISBN (Electronic)	9780323957021
ISBN (Print)	9780323957052
DOIs	https://doi.org/10.1016/B978-0-323-95702-1.00251-7
State	Published - 1 Jan 2025

Keywords

Counseling
Exertional rhabdomyolysis
Fatty acid oxidation defects
Genetic analysis
Genetic susceptibility
Glycogen storage diseases
Glycogenosis
McArdle disease
Metabolic myopathy
Mitochondrial myopathies
Muscular dystrophies
Rhabdomyolysis
Skeletal muscle breakdown
Sports

Access to Document

10.1016/B978-0-323-95702-1.00251-7

Cite this

@inbook{8cb8d0771fe54bdb805a5c2e635343c9,

title = "A Clinical Approach to Rhabdomyolysis",

abstract = "Rhabdomyolysis is a medical emergency characterized by acute skeletal muscle breakdown with a sudden strong rise and subsequent fall of serum creatine kinase (CK) levels. Rhabdomyolysis events are provoked by exposure to external triggers, sometimes in combination with an increased genetic susceptibility. In this chapter, we will provide a summary on the etiology of exertional rhabdomyolysis and an overview of the triggers and genetic susceptibilities in adults with rhabdomyolysis, summarize the (sub) acute management of patients with exertional rhabdomyolysis, present a diagnostic approach to patients with exertional rhabdomyolysis, and provide recommendations for daily activities and sports after an episode of rhabdomyolysis to prevent a recurrent episode.",

keywords = "Counseling, Exertional rhabdomyolysis, Fatty acid oxidation defects, Genetic analysis, Genetic susceptibility, Glycogen storage diseases, Glycogenosis, McArdle disease, Metabolic myopathy, Mitochondrial myopathies, Muscular dystrophies, Rhabdomyolysis, Skeletal muscle breakdown, Sports",

author = "Nicol Voermans and Salman Bhai and Nick Kruijt and Felix Kleefeld and Stemmerik, \{Mads Godtfeldt\} and Gina Ravenscroft and Francis O'Connor and Pascal Laforet and John Vissing",

note = "Publisher Copyright: {\textcopyright} 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.",

year = "2025",

month = jan,

day = "1",

doi = "10.1016/B978-0-323-95702-1.00251-7",

language = "English",

isbn = "9780323957052",

pages = "V4:448--V4:459",

booktitle = "Encyclopedia of the Neurological Sciences",

publisher = "Elsevier",

}

TY - CHAP

T1 - A Clinical Approach to Rhabdomyolysis

AU - Voermans, Nicol

AU - Bhai, Salman

AU - Kruijt, Nick

AU - Kleefeld, Felix

AU - Stemmerik, Mads Godtfeldt

AU - Ravenscroft, Gina

AU - O'Connor, Francis

AU - Laforet, Pascal

AU - Vissing, John

PY - 2025/1/1

Y1 - 2025/1/1

N2 - Rhabdomyolysis is a medical emergency characterized by acute skeletal muscle breakdown with a sudden strong rise and subsequent fall of serum creatine kinase (CK) levels. Rhabdomyolysis events are provoked by exposure to external triggers, sometimes in combination with an increased genetic susceptibility. In this chapter, we will provide a summary on the etiology of exertional rhabdomyolysis and an overview of the triggers and genetic susceptibilities in adults with rhabdomyolysis, summarize the (sub) acute management of patients with exertional rhabdomyolysis, present a diagnostic approach to patients with exertional rhabdomyolysis, and provide recommendations for daily activities and sports after an episode of rhabdomyolysis to prevent a recurrent episode.

AB - Rhabdomyolysis is a medical emergency characterized by acute skeletal muscle breakdown with a sudden strong rise and subsequent fall of serum creatine kinase (CK) levels. Rhabdomyolysis events are provoked by exposure to external triggers, sometimes in combination with an increased genetic susceptibility. In this chapter, we will provide a summary on the etiology of exertional rhabdomyolysis and an overview of the triggers and genetic susceptibilities in adults with rhabdomyolysis, summarize the (sub) acute management of patients with exertional rhabdomyolysis, present a diagnostic approach to patients with exertional rhabdomyolysis, and provide recommendations for daily activities and sports after an episode of rhabdomyolysis to prevent a recurrent episode.

KW - Counseling

KW - Exertional rhabdomyolysis

KW - Fatty acid oxidation defects

KW - Genetic analysis

KW - Genetic susceptibility

KW - Glycogen storage diseases

KW - Glycogenosis

KW - McArdle disease

KW - Metabolic myopathy

KW - Mitochondrial myopathies

KW - Muscular dystrophies

KW - Rhabdomyolysis

KW - Skeletal muscle breakdown

KW - Sports

UR - https://www.scopus.com/pages/publications/105028843820

U2 - 10.1016/B978-0-323-95702-1.00251-7

DO - 10.1016/B978-0-323-95702-1.00251-7

M3 - Chapter

AN - SCOPUS:105028843820

SN - 9780323957052

SP - V4:448-V4:459

BT - Encyclopedia of the Neurological Sciences

PB - Elsevier

ER -

A Clinical Approach to Rhabdomyolysis

Abstract

Keywords

Access to Document

Fingerprint

Cite this