A comparison of stool enteropathogen detection by semiquantitative PCR in adults with acute travelers’ diarrhea before and 3 weeks after successful antibiotic treatment

Michele D. Tisdale; David R. Tribble; Kalyani Telu; Jamie A. Fraser; Patrick Connor; Cliff Philip; Elizabeth Odundo; Faviola Reyes; Mark P. Simons; Brett Swierczewski; Stephen Lizewski; Jie Liu; Eric Houpt; Mark S. Riddle; Tahaniyat Lalani

doi:10.1093/ofid/ofz187

A comparison of stool enteropathogen detection by semiquantitative PCR in adults with acute travelers’ diarrhea before and 3 weeks after successful antibiotic treatment

Michele D. Tisdale^*, David R. Tribble, Kalyani Telu, Jamie A. Fraser, Patrick Connor, Cliff Philip, Elizabeth Odundo, Faviola Reyes, Mark P. Simons, Brett Swierczewski, Stephen Lizewski, Jie Liu, Eric Houpt, Mark S. Riddle, Tahaniyat Lalani

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Weevaluatedstoolenteropathogendetectionbysemiquantitative polymerase chain reaction (PCR) in 108 subjects with travelers’ diarrhea before and 3 weeks after treatment. Stool samples from 21 subjects were positive for the same pathogen species at both visits. We discuss factors that should be considered when interpreting stool PCR data after treatment.

Original language	English
Journal	Open Forum Infectious Diseases
Volume	6
Issue number	5
DOIs	https://doi.org/10.1093/ofid/ofz187
State	Published - 1 May 2019

Keywords

Infectious disease
Military
PCR
Travelers’ diarrhea

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Tisdale, M. D., Tribble, D. R., Telu, K., Fraser, J. A., Connor, P., Philip, C., Odundo, E., Reyes, F., Simons, M. P., Swierczewski, B., Lizewski, S., Liu, J., Houpt, E., Riddle, M. S., & Lalani, T. (2019). A comparison of stool enteropathogen detection by semiquantitative PCR in adults with acute travelers’ diarrhea before and 3 weeks after successful antibiotic treatment. Open Forum Infectious Diseases, 6(5). https://doi.org/10.1093/ofid/ofz187

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abstract = "Weevaluatedstoolenteropathogendetectionbysemiquantitative polymerase chain reaction (PCR) in 108 subjects with travelers{\textquoteright} diarrhea before and 3 weeks after treatment. Stool samples from 21 subjects were positive for the same pathogen species at both visits. We discuss factors that should be considered when interpreting stool PCR data after treatment.",

keywords = "Infectious disease, Military, PCR, Travelers{\textquoteright} diarrhea",

author = "Tisdale, {Michele D.} and Tribble, {David R.} and Kalyani Telu and Fraser, {Jamie A.} and Patrick Connor and Cliff Philip and Elizabeth Odundo and Faviola Reyes and Simons, {Mark P.} and Brett Swierczewski and Stephen Lizewski and Jie Liu and Eric Houpt and Riddle, {Mark S.} and Tahaniyat Lalani",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2019. Published by Oxford University Press on behalf of Infectious Diseases Society of America.",

year = "2019",

month = may,

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doi = "10.1093/ofid/ofz187",

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Tisdale, MD, Tribble, DR, Telu, K, Fraser, JA, Connor, P, Philip, C, Odundo, E, Reyes, F, Simons, MP, Swierczewski, B, Lizewski, S, Liu, J, Houpt, E, Riddle, MS & Lalani, T 2019, 'A comparison of stool enteropathogen detection by semiquantitative PCR in adults with acute travelers’ diarrhea before and 3 weeks after successful antibiotic treatment', Open Forum Infectious Diseases, vol. 6, no. 5. https://doi.org/10.1093/ofid/ofz187

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T1 - A comparison of stool enteropathogen detection by semiquantitative PCR in adults with acute travelers’ diarrhea before and 3 weeks after successful antibiotic treatment

AU - Tisdale, Michele D.

AU - Tribble, David R.

AU - Telu, Kalyani

AU - Fraser, Jamie A.

AU - Connor, Patrick

AU - Philip, Cliff

AU - Odundo, Elizabeth

AU - Reyes, Faviola

AU - Simons, Mark P.

AU - Swierczewski, Brett

AU - Lizewski, Stephen

AU - Liu, Jie

AU - Houpt, Eric

AU - Riddle, Mark S.

AU - Lalani, Tahaniyat

PY - 2019/5/1

Y1 - 2019/5/1

N2 - Weevaluatedstoolenteropathogendetectionbysemiquantitative polymerase chain reaction (PCR) in 108 subjects with travelers’ diarrhea before and 3 weeks after treatment. Stool samples from 21 subjects were positive for the same pathogen species at both visits. We discuss factors that should be considered when interpreting stool PCR data after treatment.

AB - Weevaluatedstoolenteropathogendetectionbysemiquantitative polymerase chain reaction (PCR) in 108 subjects with travelers’ diarrhea before and 3 weeks after treatment. Stool samples from 21 subjects were positive for the same pathogen species at both visits. We discuss factors that should be considered when interpreting stool PCR data after treatment.

KW - Infectious disease

KW - Military

KW - PCR

KW - Travelers’ diarrhea

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DO - 10.1093/ofid/ofz187

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VL - 6

JO - Open Forum Infectious Diseases

JF - Open Forum Infectious Diseases

IS - 5

ER -

A comparison of stool enteropathogen detection by semiquantitative PCR in adults with acute travelers’ diarrhea before and 3 weeks after successful antibiotic treatment

Abstract

Keywords

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