A discussion of heat generation during a fever

Weidong Zhou; Lance A. Liotta; Emanuel F. Petricoin

A discussion of heat generation during a fever

Weidong Zhou^*, Lance A. Liotta, Emanuel F. Petricoin

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Fever can be caused by pathogen infection. We analyze the thermogenesis mechanism and reveal that heat is naturally generated during the immune system’s fight against pathogen infection. Particularly, the heat production by reactive oxygen species that originates in the respiratory burst significantly contributes to the fever development. This analysis can help address mechanisms of SARS-CoV-2 pathogenesis or provide a foundation for future mechanistic inquiries.

Original language	English
Pages (from-to)	103-106
Number of pages	4
Journal	Current Topics in Peptide and Protein Research
Volume	23
State	Published - 2022
Externally published	Yes

Keywords

SARS-CoV-2
fever
reactive oxygen species
respiratory burst
thermogenesis

Cite this

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title = "A discussion of heat generation during a fever",

abstract = "Fever can be caused by pathogen infection. We analyze the thermogenesis mechanism and reveal that heat is naturally generated during the immune system{\textquoteright}s fight against pathogen infection. Particularly, the heat production by reactive oxygen species that originates in the respiratory burst significantly contributes to the fever development. This analysis can help address mechanisms of SARS-CoV-2 pathogenesis or provide a foundation for future mechanistic inquiries.",

keywords = "SARS-CoV-2, fever, reactive oxygen species, respiratory burst, thermogenesis",

author = "Weidong Zhou and Liotta, {Lance A.} and Petricoin, {Emanuel F.}",

year = "2022",

language = "English",

volume = "23",

pages = "103--106",

journal = "Current Topics in Peptide and Protein Research",

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TY - JOUR

T1 - A discussion of heat generation during a fever

AU - Zhou, Weidong

AU - Liotta, Lance A.

AU - Petricoin, Emanuel F.

PY - 2022

Y1 - 2022

N2 - Fever can be caused by pathogen infection. We analyze the thermogenesis mechanism and reveal that heat is naturally generated during the immune system’s fight against pathogen infection. Particularly, the heat production by reactive oxygen species that originates in the respiratory burst significantly contributes to the fever development. This analysis can help address mechanisms of SARS-CoV-2 pathogenesis or provide a foundation for future mechanistic inquiries.

AB - Fever can be caused by pathogen infection. We analyze the thermogenesis mechanism and reveal that heat is naturally generated during the immune system’s fight against pathogen infection. Particularly, the heat production by reactive oxygen species that originates in the respiratory burst significantly contributes to the fever development. This analysis can help address mechanisms of SARS-CoV-2 pathogenesis or provide a foundation for future mechanistic inquiries.

KW - SARS-CoV-2

KW - fever

KW - reactive oxygen species

KW - respiratory burst

KW - thermogenesis

UR - http://www.scopus.com/inward/record.url?scp=85150510999&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:85150510999

SN - 0972-4524

VL - 23

SP - 103

EP - 106

JO - Current Topics in Peptide and Protein Research

JF - Current Topics in Peptide and Protein Research

ER -

A discussion of heat generation during a fever

Abstract

Keywords

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