TY - JOUR
T1 - A Rare Cause of Dysphagia and Weight Loss
AU - Gyorffy, Janelle B.
AU - Marowske, Johanna
AU - Gancayco, John
N1 - Publisher Copyright:
© 2018 The Author(s). Published by S. Karger AG, Basel.
PY - 2018/9/1
Y1 - 2018/9/1
N2 - Mixed connective tissue disease (MCTD) is a rare connective tissue disorder with clinical features that overlap with systemic lupus erythematous, systemic sclerosis, and polymyositis. We report the case of a patient who presented with dysphagia, 25-lb weight loss, difficulty opening her mouth, and joint pain. Dysphagia workup showed a normal barium swallow and normal-appearing EGD but esophageal manometry consistent with severe dysmotility. Through further laboratory and imaging studies, the patient met the diagnostic criteria for MCTD. She had marked improvement in her dysphagia with steroids, biologic therapy, and intravenous immunoglobulin.
AB - Mixed connective tissue disease (MCTD) is a rare connective tissue disorder with clinical features that overlap with systemic lupus erythematous, systemic sclerosis, and polymyositis. We report the case of a patient who presented with dysphagia, 25-lb weight loss, difficulty opening her mouth, and joint pain. Dysphagia workup showed a normal barium swallow and normal-appearing EGD but esophageal manometry consistent with severe dysmotility. Through further laboratory and imaging studies, the patient met the diagnostic criteria for MCTD. She had marked improvement in her dysphagia with steroids, biologic therapy, and intravenous immunoglobulin.
KW - Esophageal dysmotility
KW - High-resolution esophageal manometry
KW - Mixed connective tissue disease
UR - http://www.scopus.com/inward/record.url?scp=85056095734&partnerID=8YFLogxK
U2 - 10.1159/000493919
DO - 10.1159/000493919
M3 - Article
AN - SCOPUS:85056095734
SN - 1662-0631
VL - 12
SP - 640
EP - 645
JO - Case Reports in Gastroenterology
JF - Case Reports in Gastroenterology
IS - 3
ER -