@article{41517b859a08409989d3805b0df4d968,
title = "A review of diffuse hemispheric glioma, H3 G34-mutant disease development, DNA repair, microenvironment, and treatments on the horizon",
abstract = "Diffuse hemispheric glioma H3 G34-mutant is primarily diagnosed in adolescents/young adults. While molecular diagnostics have improved, cellular mechanisms that drive tumor progression and therapy resistance are poorly understood. Combining previous published studies with findings from the 2024 NIH G34-mutant symposium aid in summarizing translational and clinical updates on disease development, cellular repair processes, and the immune microenvironment. This collective work is meant to outline opportunities for treatment and prolonged survival.",
author = "Cameron Crowell and Ziwen Zhu and Yingxiang Li and Varela, {Maria L.} and Quinn Ostrom and Cimino, {Patrick J.} and Patel, {Sohil H.} and Baker, {Suzanne J.} and Chetan Bettegowda and Houtan Noushmehr and Kleinman, {Claudia L.} and Laura Canty and Cruzeiro, {Gustavo Alencastro Veiga} and Anandani Nellan and Oren Becher and Davidson, {Tom B.} and Dolores Hambardzumyan and Adam Green and Robert Thorne and Kelli Wilson and Brett Theeler and Jason Gregory and Peter Mathen and Nadia Biassou and Sheila McThenia and Craig Erker and Robert Galvin and Ariane Soldatos and Lowenstein, {Pedro R.} and Castro, {Maria G.} and Sadhana Jackson",
year = "2025",
doi = "10.1038/s41698-025-01070-w",
language = "American English",
volume = "9",
journal = "npj Precision Oncology",
issn = "2397-768X",
publisher = "Nature Research",
number = "1",
}