@article{8b6abb99620d42009194532b43f3f07f,
title = "A site assessment tool for inpatient controlled human infection models for enteric disease pathogens",
abstract = "The use of the controlled human infection model to facilitate product development and to advance understanding of host-pathogen interactions is of increasing interest. While administering a virulent (or infective) organism to a susceptible host necessitates an ongoing evaluation of safety and ethical considerations, a central theme in conducting these studies in a safe and ethical manner that yields actionable data is their conduct in facilities well-suited to address their unique attributes. To that end, we have developed a framework for evaluating potential sites in which to conduct inpatient enteric controlled human infection model to ensure consistency and increase the likelihood of success.",
keywords = "Controlled human infection models, diarrheal disease, enteric infection, vaccine",
author = "Porter, {Chad K.} and Detizio, {Katherine J.} and Nicole Maier and Testa, {Kayla J.} and Talaat, {Kawsar R.} and Chen, {Wilbur H.} and Lyon, {Caroline E.} and Gutierrez, {Ramiro L.} and Robert Frenck and Isidean, {Sandra D.} and Kaminski, {Robert W.} and Alcala, {Ashley N.} and Kurt Hanevik and Frederick Sawe and Kirkpatrick, {Beth D.} and {Louis Bourgeois}, A.",
note = "Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported, in part, by the Bill & Melinda Gates Foundation (OPP1112376). Under the grant conditions of the Foundation, a Creative Commons Attribution 4.0 Generic License has already been assigned to the Author Accepted Manuscript version that might arise from this submission. Publisher Copyright: {\textcopyright} The Author(s) 2021.",
year = "2022",
month = feb,
doi = "10.1177/17407745211052473",
language = "English",
volume = "19",
pages = "116--118",
journal = "Clinical Trials",
issn = "1740-7745",
number = "1",
}