TY - JOUR
T1 - Activity of the diaminopyrimidine AR-709 against recently collected multidrug-resistant isolates of invasive Streptococcus pneumoniae from North America
AU - Ressner, Roseanne A.
AU - Moore, Matthew R.
AU - Jorgensen, James H.
PY - 2008/3
Y1 - 2008/3
N2 - Broth microdilution was used to determine the MICs of AR-709 and comparator antimicrobial agents for 224 invasive multidrug-resistant isolates of Streptococcus pneumoniae. AR-709 was highly active, with a MIC50 of 0.25 μg/ml, a MIC90 of 0.5 μg/ml, and a range of ≤0.008 μg/ml to 1 μg/ml.
AB - Broth microdilution was used to determine the MICs of AR-709 and comparator antimicrobial agents for 224 invasive multidrug-resistant isolates of Streptococcus pneumoniae. AR-709 was highly active, with a MIC50 of 0.25 μg/ml, a MIC90 of 0.5 μg/ml, and a range of ≤0.008 μg/ml to 1 μg/ml.
UR - http://www.scopus.com/inward/record.url?scp=40549097453&partnerID=8YFLogxK
U2 - 10.1128/AAC.01387-07
DO - 10.1128/AAC.01387-07
M3 - Article
C2 - 18180346
AN - SCOPUS:40549097453
SN - 0066-4804
VL - 52
SP - 1147
EP - 1149
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
IS - 3
ER -