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An adaptive platform trial for evaluating treatments in patients with life-threatening hemorrhage from traumatic injuries: Ethical and US regulatory considerations

  • Sara F. Goldkind*
  • , Laura R. Brosch
  • , Roger J. Lewis
  • , Claudia Pedroza
  • , Philip C. Spinella
  • , Kabir Yadav
  • , Stacy A. Shackelford
  • , John B. Holcomb
  • *Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

5 Scopus citations
Original languageEnglish
Pages (from-to)S255-S265
JournalTransfusion
Volume62
Issue numberS1
DOIs
StatePublished - Aug 2022

Keywords

  • adaptive trials
  • clinical trial design
  • exception from informed consent
  • hemorrhagic shock
  • medical ethics
  • platform trials
  • trauma resuscitation

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