Antibiotic‐Associated Fulminant Pseudomembranous Colitis without Toxic Megacolon

Barry E. Herman, John Vargo, W. Stephen Phillips, W. Brian Sweeney, Rocco J. Volpe

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Presented is a middle‐aged male who developed a fulminant case of antibiotic‐associated pseudomembranous colitis characterized by leukocytosis, hypoal‐buminemia, ascites, and anasarca without toxic mega‐colon. The patient responded slowly to medical therapy consisting of intravenous metronidazole, oral vancomycin, and parenteral nutrition. Subsequently, cholestyramine was administered. A review of the literature concerning similar cases of fulminant pseudomembranous colitis is presented.

Original languageEnglish
Pages (from-to)1816-1819
Number of pages4
JournalAmerican Journal of Gastroenterology
Issue number12
StatePublished - Dec 1992
Externally publishedYes


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