Antiphospholipid syndrome in a 21-year-old with klinefelter syndrome

George R. Mount, Jonathan D. Roebuck

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


We describe a patient with Klinefelter syndrome presenting with recurrent arterial thromboses secondary to the antiphospholipid syndrome. Previous case reports noted association of Klinefelter syndrome with systemic lupus erythematosus including some cases with antiphospholipid syndrome. Clinicians should consider autoimmune processes, including the antiphospholipid syndrome, when patients with Klinefelter syndrome present with recurrent thrombosis or additional features of a systemic autoimmune disorder.

Original languageEnglish
Pages (from-to)27-28
Number of pages2
JournalJournal of Clinical Rheumatology
Issue number1
StatePublished - Jan 2009
Externally publishedYes


  • Antiphospholipid syndrome
  • Klinefelter syndrome
  • Systemic lupus erythematosus
  • Thrombosis


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