ANX7 as a bio-marker in prostate and breast cancer progression

Meera Srivastava; Lukas Bubendorf; Lisa Nolan; Mirta Glasman; Ximena Leighton; Georgina Miller; Wilfred Fehrle; Mark Raffeld; Ofer Eidelman; Olli P. Kallioniemi; Shiv Srivastava; Harvey B. Pollard

doi:10.1155/2001/239602

ANX7 as a bio-marker in prostate and breast cancer progression

Meera Srivastava^*, Lukas Bubendorf, Lisa Nolan, Mirta Glasman, Ximena Leighton, Georgina Miller, Wilfred Fehrle, Mark Raffeld, Ofer Eidelman, Olli P. Kallioniemi, Shiv Srivastava, Harvey B. Pollard

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

The ANX7 gene codes for a Ca²⁺-activated GTPase, which has been implicated in both exocytotic secretion in cells and control of growth. In this review, we summarize information regarding increased tumor frequency in the Anx7 knockout mice, ANX7 growth suppression of human cancer cell lines, and ANX7 expression in human tumor tissue micro-arrays. The loss of ANX7 is significant in metastatic and hormone refractory prostate cancer compared to benign prostatic hyperplasia. In addition, ANX7 expression has prognostic value for predicting survival of breast cancer patients.

Original language	English
Pages (from-to)	115-120
Number of pages	6
Journal	Disease Markers
Volume	17
Issue number	2
DOIs	https://doi.org/10.1155/2001/239602
State	Published - 2001
Externally published	Yes

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title = "ANX7 as a bio-marker in prostate and breast cancer progression",

abstract = "The ANX7 gene codes for a Ca2+-activated GTPase, which has been implicated in both exocytotic secretion in cells and control of growth. In this review, we summarize information regarding increased tumor frequency in the Anx7 knockout mice, ANX7 growth suppression of human cancer cell lines, and ANX7 expression in human tumor tissue micro-arrays. The loss of ANX7 is significant in metastatic and hormone refractory prostate cancer compared to benign prostatic hyperplasia. In addition, ANX7 expression has prognostic value for predicting survival of breast cancer patients.",

author = "Meera Srivastava and Lukas Bubendorf and Lisa Nolan and Mirta Glasman and Ximena Leighton and Georgina Miller and Wilfred Fehrle and Mark Raffeld and Ofer Eidelman and Kallioniemi, {Olli P.} and Shiv Srivastava and Pollard, {Harvey B.}",

year = "2001",

doi = "10.1155/2001/239602",

language = "English",

volume = "17",

pages = "115--120",

journal = "Disease Markers",

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T1 - ANX7 as a bio-marker in prostate and breast cancer progression

AU - Srivastava, Meera

AU - Bubendorf, Lukas

AU - Nolan, Lisa

AU - Glasman, Mirta

AU - Leighton, Ximena

AU - Miller, Georgina

AU - Fehrle, Wilfred

AU - Raffeld, Mark

AU - Eidelman, Ofer

AU - Kallioniemi, Olli P.

AU - Srivastava, Shiv

AU - Pollard, Harvey B.

PY - 2001

Y1 - 2001

N2 - The ANX7 gene codes for a Ca2+-activated GTPase, which has been implicated in both exocytotic secretion in cells and control of growth. In this review, we summarize information regarding increased tumor frequency in the Anx7 knockout mice, ANX7 growth suppression of human cancer cell lines, and ANX7 expression in human tumor tissue micro-arrays. The loss of ANX7 is significant in metastatic and hormone refractory prostate cancer compared to benign prostatic hyperplasia. In addition, ANX7 expression has prognostic value for predicting survival of breast cancer patients.

AB - The ANX7 gene codes for a Ca2+-activated GTPase, which has been implicated in both exocytotic secretion in cells and control of growth. In this review, we summarize information regarding increased tumor frequency in the Anx7 knockout mice, ANX7 growth suppression of human cancer cell lines, and ANX7 expression in human tumor tissue micro-arrays. The loss of ANX7 is significant in metastatic and hormone refractory prostate cancer compared to benign prostatic hyperplasia. In addition, ANX7 expression has prognostic value for predicting survival of breast cancer patients.

UR - http://www.scopus.com/inward/record.url?scp=0034799216&partnerID=8YFLogxK

U2 - 10.1155/2001/239602

DO - 10.1155/2001/239602

M3 - Article

C2 - 11673658

AN - SCOPUS:0034799216

SN - 0278-0240

VL - 17

SP - 115

EP - 120

JO - Disease Markers

JF - Disease Markers

IS - 2

ER -

ANX7 as a bio-marker in prostate and breast cancer progression

Abstract

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