Arterial and venous repair with vascular clips: Comparison with suture closure

A. Leppaniemi*, D. Wherry, E. Pikoulis, H. Hufnagel, C. Waasdorp, N. Fishback, N. Rich

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

63 Scopus citations


Purpose: Nonpenetrating, arcuate-legged titanium vascular closure staple (VCS) clips were initially developed for microvascular anastomoses with little experience of their use in larger vessels. The purpose of this study was to compare the VCS clips with standard suture closure of arteriotomies and venotomies in common iliac vessels of pigs. Methods: In nine pigs, longitudinal 1 cm iliac arterial and venous incisions were repaired with VCS clips on one side and continuous 6-0 polypropylene suture on the other, and the macroscopic and microscopic results were assessed after 3 months. Results: The time required for vessel repair was significantly shorter with clips than with sutures both in arteries (51 ± 9 vs 414 ± 36 seconds) and in veins (100 ± 32 vs 439 ± 45 seconds). There was no significant difference in the inner diameters, intimal thickness, or intima-to-media height ratios of the arteries or veins after either method of closure. Conclusions: Repair of 1 cm incisions in small-diameter arteries and veins with VCS clips results in wound healing as good as that achieved with standard suture closure, when assessed for patency, leakage, degree of narrowing, and intimal reaction. The time required for dip closure is considerably shorter than for suture closure.

Original languageEnglish
Pages (from-to)24-28
Number of pages5
JournalJournal of Vascular Surgery
Issue number1
StatePublished - 1997
Externally publishedYes


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