Assessment of cadaveric organ viability during pulsatile perfusion using infrared imaging

Alexander M. Gorbach, David B. Leeser, Hengliang Wang, Douglas K. Tadaki, Carlos Fernandez, David Destephano, Douglas Hale, Allan D. Kirk, Fred A. Gage, Eric A. Elster

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Assessment of pulsatile perfusion (PP) is limited to measurements of flow (V) and resistance (R). We investigated infrared (IR) imaging during PP as a means for precise organ assessment. IR was used to monitor 10 porcine kidneys during 18 hr of PP in an uncontrolled Donation after Cardiac Death model. An IR camera (Lockheed Martin) was focused on the anterior surfaces of the kidneys. The degree of temperature homogeneity was compared with standard measurements of V and R. IR thermal images correlated with V and R (R≤0.92, P<0.001). IR detected an increase in homogeneity during PP by comparing standard deviation differences before and after PP (P≤0.002), which was not evident by standard measurements of V and R. Finally, IR assessment allowed for measurement of dynamic changes in perfusion.

Original languageEnglish
Pages (from-to)1163-1166
Number of pages4
JournalTransplantation
Volume87
Issue number8
DOIs
StatePublished - 27 Apr 2009
Externally publishedYes

Keywords

  • Infrared imaging
  • Pulsatile perfusion
  • Viability

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