Assessment of cadaveric organ viability during pulsatile perfusion using infrared imaging

Alexander M. Gorbach; David B. Leeser; Hengliang Wang; Douglas K. Tadaki; Carlos Fernandez; David Destephano; Douglas Hale; Allan D. Kirk; Fred A. Gage; Eric A. Elster

doi:10.1097/TP.0b013e31819e3e02

Assessment of cadaveric organ viability during pulsatile perfusion using infrared imaging

Alexander M. Gorbach, David B. Leeser, Hengliang Wang, Douglas K. Tadaki, Carlos Fernandez, David Destephano, Douglas Hale, Allan D. Kirk, Fred A. Gage, Eric A. Elster

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10 Scopus citations

Abstract

Assessment of pulsatile perfusion (PP) is limited to measurements of flow (V) and resistance (R). We investigated infrared (IR) imaging during PP as a means for precise organ assessment. IR was used to monitor 10 porcine kidneys during 18 hr of PP in an uncontrolled Donation after Cardiac Death model. An IR camera (Lockheed Martin) was focused on the anterior surfaces of the kidneys. The degree of temperature homogeneity was compared with standard measurements of V and R. IR thermal images correlated with V and R (R≤0.92, P<0.001). IR detected an increase in homogeneity during PP by comparing standard deviation differences before and after PP (P≤0.002), which was not evident by standard measurements of V and R. Finally, IR assessment allowed for measurement of dynamic changes in perfusion.

Original language	English
Pages (from-to)	1163-1166
Number of pages	4
Journal	Transplantation
Volume	87
Issue number	8
DOIs	https://doi.org/10.1097/TP.0b013e31819e3e02
State	Published - 27 Apr 2009
Externally published	Yes

Keywords

Infrared imaging
Pulsatile perfusion
Viability

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10.1097/TP.0b013e31819e3e02

Cite this

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title = "Assessment of cadaveric organ viability during pulsatile perfusion using infrared imaging",

abstract = "Assessment of pulsatile perfusion (PP) is limited to measurements of flow (V) and resistance (R). We investigated infrared (IR) imaging during PP as a means for precise organ assessment. IR was used to monitor 10 porcine kidneys during 18 hr of PP in an uncontrolled Donation after Cardiac Death model. An IR camera (Lockheed Martin) was focused on the anterior surfaces of the kidneys. The degree of temperature homogeneity was compared with standard measurements of V and R. IR thermal images correlated with V and R (R≤0.92, P<0.001). IR detected an increase in homogeneity during PP by comparing standard deviation differences before and after PP (P≤0.002), which was not evident by standard measurements of V and R. Finally, IR assessment allowed for measurement of dynamic changes in perfusion.",

keywords = "Infrared imaging, Pulsatile perfusion, Viability",

author = "Gorbach, {Alexander M.} and Leeser, {David B.} and Hengliang Wang and Tadaki, {Douglas K.} and Carlos Fernandez and David Destephano and Douglas Hale and Kirk, {Allan D.} and Gage, {Fred A.} and Elster, {Eric A.}",

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T1 - Assessment of cadaveric organ viability during pulsatile perfusion using infrared imaging

AU - Gorbach, Alexander M.

AU - Leeser, David B.

AU - Wang, Hengliang

AU - Tadaki, Douglas K.

AU - Fernandez, Carlos

AU - Destephano, David

AU - Hale, Douglas

AU - Kirk, Allan D.

AU - Gage, Fred A.

AU - Elster, Eric A.

PY - 2009/4/27

Y1 - 2009/4/27

N2 - Assessment of pulsatile perfusion (PP) is limited to measurements of flow (V) and resistance (R). We investigated infrared (IR) imaging during PP as a means for precise organ assessment. IR was used to monitor 10 porcine kidneys during 18 hr of PP in an uncontrolled Donation after Cardiac Death model. An IR camera (Lockheed Martin) was focused on the anterior surfaces of the kidneys. The degree of temperature homogeneity was compared with standard measurements of V and R. IR thermal images correlated with V and R (R≤0.92, P<0.001). IR detected an increase in homogeneity during PP by comparing standard deviation differences before and after PP (P≤0.002), which was not evident by standard measurements of V and R. Finally, IR assessment allowed for measurement of dynamic changes in perfusion.

AB - Assessment of pulsatile perfusion (PP) is limited to measurements of flow (V) and resistance (R). We investigated infrared (IR) imaging during PP as a means for precise organ assessment. IR was used to monitor 10 porcine kidneys during 18 hr of PP in an uncontrolled Donation after Cardiac Death model. An IR camera (Lockheed Martin) was focused on the anterior surfaces of the kidneys. The degree of temperature homogeneity was compared with standard measurements of V and R. IR thermal images correlated with V and R (R≤0.92, P<0.001). IR detected an increase in homogeneity during PP by comparing standard deviation differences before and after PP (P≤0.002), which was not evident by standard measurements of V and R. Finally, IR assessment allowed for measurement of dynamic changes in perfusion.

KW - Infrared imaging

KW - Pulsatile perfusion

KW - Viability

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Assessment of cadaveric organ viability during pulsatile perfusion using infrared imaging

Abstract

Keywords

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