Association of multinodular goiter with breast carcinoma: Cowden’s disease1

R. D. Michaels, K. M.M. Shakir*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Cowden’s Disease or multiple hamartoma syndrome is an autosomal dominant genodermatosis associated with abnormalities of the breast, thyroid gland, gastrointestinal tract and genitourinary system. A large percentage of these patients have goiters or other thyroid abnormalities. Physicians should consider the diagnosis of Cowden’s disease in patients presenting with thyroid disease and skin lesions such as papules or skin tags and if present these subjects should be screened for other malignancies associated with this disease.

Original languageEnglish
Pages (from-to)909-911
Number of pages3
JournalJournal of Endocrinological Investigation: Official Journal of the Italian Society of Endocrinology
Issue number11
StatePublished - Dec 1993
Externally publishedYes


  • Cowden’s disease
  • breast carcinoma
  • multinodular goiter


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