Automated reconstruction of the cerebral cortex in multiple sclerosis patients

N. Shiee*, P. L. Bazin, Daniel S. Reich, D. L. Pham

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

Although cortical atrophy in multiple sclerosis (MS) has been reported in the literature, most cortical reconstruction techniques do not account for lesions. In this work, we propose an automated pipeline for cortical reconstruction from magnetic resonance brain images with MS lesions. The pipeline extends previously well validated methods to allow for the presence of lesions and to accommodate multichannel imaging. We validate this approach on simulated and real images. Application of the pipeline to 103 MS brains produces thickness measurements that agree well with the literature.

Original languageEnglish
Title of host publicationProceedings - 2009 IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro, ISBI 2009
Pages1334-1337
Number of pages4
DOIs
StatePublished - 2009
Event2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009 - Boston, MA, United States
Duration: 28 Jun 20091 Jul 2009

Publication series

NameProceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009

Conference

Conference2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009
Country/TerritoryUnited States
CityBoston, MA
Period28/06/091/07/09

Keywords

  • Cortical reconstruction
  • Cortical thickness
  • Lesion segmentation
  • Multiple sclerosis

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