Avian Influenza: An Overview and Clinical Status

John L. Kiley; Heather Yun

doi:10.1007/s11908-024-00850-y

Avian Influenza: An Overview and Clinical Status

John L. Kiley^*, Heather Yun

^*Corresponding author for this work

Medicine

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Purpose of Review: 2024 saw the outbreak of a strain of highly pathogenic avian influenza with intermittent transmission to humans. This review will consider the landscape of avian influenza, the role migratory birds and cattle play in transmission, and our understanding of the current outbreak in humans. Recent Findings: While cases of human avian influenza have fortunately continued to be relatively low, the evidence that continued circulation in migratory and domestic poultry flocks combined with spillover into bovine herds support further efforts to understand this outbreak and develop mitigation strategies like vaccines and therapeutics. Summary: Highly pathogenic avian influenza is likely to remain a critical target for epidemiologic surveillance along with further development of new mitigation strategies.

Original language	English
Article number	1
Journal	Current Infectious Disease Reports
Volume	27
Issue number	1
DOIs	https://doi.org/10.1007/s11908-024-00850-y
State	Published - Dec 2025

Keywords

Avian influenza
Bovine
Highly pathogenic avian influenza
Migratory birds
Vaccine development

Access to Document

10.1007/s11908-024-00850-y

Cite this

@article{b85271cf307c4464a18ec5e218da08d7,

title = "Avian Influenza: An Overview and Clinical Status",

abstract = "Purpose of Review: 2024 saw the outbreak of a strain of highly pathogenic avian influenza with intermittent transmission to humans. This review will consider the landscape of avian influenza, the role migratory birds and cattle play in transmission, and our understanding of the current outbreak in humans. Recent Findings: While cases of human avian influenza have fortunately continued to be relatively low, the evidence that continued circulation in migratory and domestic poultry flocks combined with spillover into bovine herds support further efforts to understand this outbreak and develop mitigation strategies like vaccines and therapeutics. Summary: Highly pathogenic avian influenza is likely to remain a critical target for epidemiologic surveillance along with further development of new mitigation strategies.",

keywords = "Avian influenza, Bovine, Highly pathogenic avian influenza, Migratory birds, Vaccine development",

author = "Kiley, {John L.} and Heather Yun",

note = "Publisher Copyright: {\textcopyright} This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2024.",

year = "2025",

month = dec,

doi = "10.1007/s11908-024-00850-y",

language = "English",

volume = "27",

journal = "Current Infectious Disease Reports",

issn = "1523-3847",

number = "1",

}

TY - JOUR

T1 - Avian Influenza

T2 - An Overview and Clinical Status

AU - Kiley, John L.

AU - Yun, Heather

N1 - Publisher Copyright: © This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2024.

PY - 2025/12

Y1 - 2025/12

N2 - Purpose of Review: 2024 saw the outbreak of a strain of highly pathogenic avian influenza with intermittent transmission to humans. This review will consider the landscape of avian influenza, the role migratory birds and cattle play in transmission, and our understanding of the current outbreak in humans. Recent Findings: While cases of human avian influenza have fortunately continued to be relatively low, the evidence that continued circulation in migratory and domestic poultry flocks combined with spillover into bovine herds support further efforts to understand this outbreak and develop mitigation strategies like vaccines and therapeutics. Summary: Highly pathogenic avian influenza is likely to remain a critical target for epidemiologic surveillance along with further development of new mitigation strategies.

AB - Purpose of Review: 2024 saw the outbreak of a strain of highly pathogenic avian influenza with intermittent transmission to humans. This review will consider the landscape of avian influenza, the role migratory birds and cattle play in transmission, and our understanding of the current outbreak in humans. Recent Findings: While cases of human avian influenza have fortunately continued to be relatively low, the evidence that continued circulation in migratory and domestic poultry flocks combined with spillover into bovine herds support further efforts to understand this outbreak and develop mitigation strategies like vaccines and therapeutics. Summary: Highly pathogenic avian influenza is likely to remain a critical target for epidemiologic surveillance along with further development of new mitigation strategies.

KW - Avian influenza

KW - Bovine

KW - Highly pathogenic avian influenza

KW - Migratory birds

KW - Vaccine development

UR - http://www.scopus.com/inward/record.url?scp=85209568409&partnerID=8YFLogxK

U2 - 10.1007/s11908-024-00850-y

DO - 10.1007/s11908-024-00850-y

M3 - Article

AN - SCOPUS:85209568409

SN - 1523-3847

VL - 27

JO - Current Infectious Disease Reports

JF - Current Infectious Disease Reports

IS - 1

M1 - 1

ER -