@article{f24aecfaa36f430fbc6bb3caf651c85d,
title = "Barrett's esophagus. A prevalent, occult complication of gastroesophageal reflux disease",
abstract = "A prospective study of patients with symptoms of gastroesophageal reflux was undertaken to determine the prevalence of Barrett's esophagus and reevaluate the diagnostic approach necessary to detect this complication. Endoscopy with mucosal biopsy was performed in 97 subjects. Twelve (12.4%) were found to have Barrett's esophagus. The sensitivity and specificity of the endoscopic and radiologic examinations for Barrett's esophagus were prospectively evaluated. Endoscopy (92%) was significantly more sensitive than radiology (24%) in detecting Barrett's esophagus (p < 0.001). The frequency and severity of reflux symptoms among patients determined to have Barrett's esophagus, reflux esophagitis, or normal esophageal biopsies were quantitatively similar in all three groups, except for significantly greater daytime heartburn in those with reflux esophagitis (p < 0.01). These data indicate that Barrett's esophagus complicates gastroesophageal reflux more often than previously believed.",
author = "Charles Winters and Spurling, {Timothy J.} and Chobanian, {Sarkis J.} and Curtis, {David J.} and Esposito, {Regina L.} and Hacker, {Joseph F.} and Johnson, {David A.} and Cruess, {David F.} and Cotelingam, {J. D.} and Gurney, {Michael S.} and Cattau, {Edward L.}",
note = "Funding Information: Received February 4, 1986. Accepted July 1, 1986. Address requests for reprints to: Charles Winters, Jr., M.D., 312 Hospital Drive, Suite 2, Madison, Tennessee 37115. Dr. Spurling{\textquoteright}s current address is Southland Medical Center, Florence, South Carolina. Dr. Cattau{\textquoteright}s current address is Division of Gastroenterology, Georgetown University, Washington, D.C. 20007. Supported by Naval Medical Command, Washington, D.C., Navy Department, CIP Protocol 84-06-2038-00. The opinions and assertions contained herein are the private ones of the authors and are not to be construed as official policy or reflecting the views of the Department of the Navy or the Department of Defense.",
year = "1987",
month = jan,
doi = "10.1016/0016-5085(87)90847-X",
language = "English",
volume = "92",
pages = "118--124",
journal = "Gastroenterology",
issn = "0016-5085",
publisher = "W.B. Saunders",
number = "1",
}