Biologic Scaffolds Composed of Extracellular Matrix for Regenerative Medicine

Michelle Scarritt, Mark Murdock, Stephen F. Badylak

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

11 Scopus citations


Mammalian biologic scaffolds composed of extracellular matrix (ECM) contain countless structural and functional moieties that have been shown to be necessary for tissue development, homeostasis, and response to injury. Biologic scaffold materials are employed in clinical medicine and their use will likely expand as regenerative medicine strategies evolve. This chapter discusses the generation and use of biologic scaffold materials for regenerative medicine applications with a focus on ECM scaffolds. The biologic properties and known functions of the individual components of the ECM, the generation of three-dimensional whole-organ scaffolds, and the federal regulation of biologic scaffolds are also discussed.

Original languageEnglish
Title of host publicationPrinciples of Regenerative Medicine
Number of pages14
ISBN (Electronic)9780128098806
ISBN (Print)9780128098936
StatePublished - 1 Jan 2018
Externally publishedYes


  • Bioscaffold
  • Extracellular matrix
  • Regenerative medicine
  • Scaffold
  • Tissue engineering


Dive into the research topics of 'Biologic Scaffolds Composed of Extracellular Matrix for Regenerative Medicine'. Together they form a unique fingerprint.

Cite this