Biomarkers of ovarian tumours

Amy V. Rapkiewicz*, Virginia Espina, Emanuel F. Petricoin, Lance A. Liotta

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

71 Scopus citations

Abstract

Ovarian cancer is one of the most aggressive gynaecological malignancies and most often the high mortality is a direct result of delays in diagnosis. The development of an ovarian cancer-specific biomarker for the early detection of disease has the capacity to improve the dismal survival rate. Currently, there are multiple investigations that are utilising both genomic and proteomic technologies to identify genes, gene products and proteins that may potentially identify diagnostic ovarian cancer biomarkers. Here, we review the studies that are involved in biomarker development for the detection of ovarian cancer.

Original languageEnglish
Pages (from-to)2604-2612
Number of pages9
JournalEuropean Journal of Cancer
Volume40
Issue number17 SPEC. ISS.
DOIs
StatePublished - Nov 2004
Externally publishedYes

Keywords

  • Biomarker
  • Cancer
  • Microarray
  • Ovarian
  • Proteomics

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