Biomarkers of ovarian tumours

Amy V. Rapkiewicz; Virginia Espina; Emanuel F. Petricoin; Lance A. Liotta

doi:10.1016/j.ejca.2004.05.021

Biomarkers of ovarian tumours

Amy V. Rapkiewicz^*, Virginia Espina, Emanuel F. Petricoin, Lance A. Liotta

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

72 Scopus citations

Abstract

Ovarian cancer is one of the most aggressive gynaecological malignancies and most often the high mortality is a direct result of delays in diagnosis. The development of an ovarian cancer-specific biomarker for the early detection of disease has the capacity to improve the dismal survival rate. Currently, there are multiple investigations that are utilising both genomic and proteomic technologies to identify genes, gene products and proteins that may potentially identify diagnostic ovarian cancer biomarkers. Here, we review the studies that are involved in biomarker development for the detection of ovarian cancer.

Original language	English
Pages (from-to)	2604-2612
Number of pages	9
Journal	European Journal of Cancer
Volume	40
Issue number	17 SPEC. ISS.
DOIs	https://doi.org/10.1016/j.ejca.2004.05.021
State	Published - Nov 2004
Externally published	Yes

Keywords

Biomarker
Cancer
Microarray
Ovarian
Proteomics

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10.1016/j.ejca.2004.05.021

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abstract = "Ovarian cancer is one of the most aggressive gynaecological malignancies and most often the high mortality is a direct result of delays in diagnosis. The development of an ovarian cancer-specific biomarker for the early detection of disease has the capacity to improve the dismal survival rate. Currently, there are multiple investigations that are utilising both genomic and proteomic technologies to identify genes, gene products and proteins that may potentially identify diagnostic ovarian cancer biomarkers. Here, we review the studies that are involved in biomarker development for the detection of ovarian cancer.",

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AU - Rapkiewicz, Amy V.

AU - Espina, Virginia

AU - Petricoin, Emanuel F.

AU - Liotta, Lance A.

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Y1 - 2004/11

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AB - Ovarian cancer is one of the most aggressive gynaecological malignancies and most often the high mortality is a direct result of delays in diagnosis. The development of an ovarian cancer-specific biomarker for the early detection of disease has the capacity to improve the dismal survival rate. Currently, there are multiple investigations that are utilising both genomic and proteomic technologies to identify genes, gene products and proteins that may potentially identify diagnostic ovarian cancer biomarkers. Here, we review the studies that are involved in biomarker development for the detection of ovarian cancer.

KW - Biomarker

KW - Cancer

KW - Microarray

KW - Ovarian

KW - Proteomics

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EP - 2612

JO - European Journal of Cancer

JF - European Journal of Cancer

IS - 17 SPEC. ISS.

ER -

Biomarkers of ovarian tumours

Abstract

Keywords

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