Biomaterials for tissue engineering applications

Timothy J. Keane, Stephen F. Badylak*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

130 Scopus citations

Abstract

With advancements in biological and engineering sciences, the definition of an ideal biomaterial has evolved over the past 50 years from a substance that is inert to one that has select bioinductive properties and integrates well with adjacent host tissue. Biomaterials are a fundamental component of tissue engineering, which aims to replace diseased, damaged, or missing tissue with reconstructed functional tissue. Most biomaterials are less than satisfactory for pediatric patients because the scaffold must adapt to the growth and development of the surrounding tissues and organs over time. The pediatric community, therefore, provides a distinct challenge for the tissue engineering community.

Original languageEnglish
Pages (from-to)112-118
Number of pages7
JournalSeminars in Pediatric Surgery
Volume23
Issue number3
DOIs
StatePublished - Jun 2014
Externally publishedYes

Keywords

  • Bioactive molecules
  • Biomaterials
  • Tissue engineering

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