Blood Pressure Targets for Patients with Hypertension and Cardiovascular Disease

Dustin Smith; Paul Seales; Sajeewane Seales

Blood Pressure Targets for Patients with Hypertension and Cardiovascular Disease

Dustin Smith^*, Paul Seales, Sajeewane Seales

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

Abstract

LOWER BP TARGETS IN PATIENTS WITH HYPERTENSION AND CARDIOVASCULAR DISEASE Outcomes (average of 4 years) Risk with standard BP target (≤ 140 to 160/90 to 100 mm Hg) Risk with lower BP target (≤ 135/85 mm Hg) NNT or NNH (95% CI) Number of participants (number of studies) Quality of evidence Total mortality 68 per 1,000 72 per 1,000 NA* 9,484 (6) Moderate Serious adverse effects 252 per 1,000 255 per 1,000 NA* 9,484 (6) Low Total CV events 127 per 1,000 113 per 1,000 NA* 9,484 (6) Low CV mortality 31 per 1,000 32 per 1,000 NA* 9,484 (6) Moderate Withdrawals because of adverse effects 7 per 1,000 60 per 1,000 19 (4 to 111) 690 (2) Very low BP= blood pressure; CI= confidence interval; CV= cardiovascular; NA= not applicable; NNH= number needed to harm; NNT= number needed to treat.*-No statistical difference in outcomes. Of those patients with hypertension, only 75 …

Original language	American English
Pages (from-to)	276
Journal	American Family Physician
Volume	98
Issue number	5
State	Published - 1 Sep 2018

Cite this

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title = "Blood Pressure Targets for Patients with Hypertension and Cardiovascular Disease",

abstract = "LOWER BP TARGETS IN PATIENTS WITH HYPERTENSION AND CARDIOVASCULAR DISEASE Outcomes (average of 4 years) Risk with standard BP target (≤ 140 to 160/90 to 100 mm Hg) Risk with lower BP target (≤ 135/85 mm Hg) NNT or NNH (95% CI) Number of participants (number of studies) Quality of evidence Total mortality 68 per 1,000 72 per 1,000 NA* 9,484 (6) Moderate Serious adverse effects 252 per 1,000 255 per 1,000 NA* 9,484 (6) Low Total CV events 127 per 1,000 113 per 1,000 NA* 9,484 (6) Low CV mortality 31 per 1,000 32 per 1,000 NA* 9,484 (6) Moderate Withdrawals because of adverse effects 7 per 1,000 60 per 1,000 19 (4 to 111) 690 (2) Very low BP= blood pressure; CI= confidence interval; CV= cardiovascular; NA= not applicable; NNH= number needed to harm; NNT= number needed to treat.*-No statistical difference in outcomes. Of those patients with hypertension, only 75 …",

author = "Dustin Smith and Paul Seales and Sajeewane Seales",

year = "2018",

month = sep,

day = "1",

language = "American English",

volume = "98",

pages = "276",

journal = "American Family Physician",

issn = "0002-838X",

publisher = "American Academy of Family Physicians",

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TY - JOUR

T1 - Blood Pressure Targets for Patients with Hypertension and Cardiovascular Disease

AU - Smith, Dustin

AU - Seales, Paul

AU - Seales, Sajeewane

PY - 2018/9/1

Y1 - 2018/9/1

N2 - LOWER BP TARGETS IN PATIENTS WITH HYPERTENSION AND CARDIOVASCULAR DISEASE Outcomes (average of 4 years) Risk with standard BP target (≤ 140 to 160/90 to 100 mm Hg) Risk with lower BP target (≤ 135/85 mm Hg) NNT or NNH (95% CI) Number of participants (number of studies) Quality of evidence Total mortality 68 per 1,000 72 per 1,000 NA* 9,484 (6) Moderate Serious adverse effects 252 per 1,000 255 per 1,000 NA* 9,484 (6) Low Total CV events 127 per 1,000 113 per 1,000 NA* 9,484 (6) Low CV mortality 31 per 1,000 32 per 1,000 NA* 9,484 (6) Moderate Withdrawals because of adverse effects 7 per 1,000 60 per 1,000 19 (4 to 111) 690 (2) Very low BP= blood pressure; CI= confidence interval; CV= cardiovascular; NA= not applicable; NNH= number needed to harm; NNT= number needed to treat.*-No statistical difference in outcomes. Of those patients with hypertension, only 75 …

AB - LOWER BP TARGETS IN PATIENTS WITH HYPERTENSION AND CARDIOVASCULAR DISEASE Outcomes (average of 4 years) Risk with standard BP target (≤ 140 to 160/90 to 100 mm Hg) Risk with lower BP target (≤ 135/85 mm Hg) NNT or NNH (95% CI) Number of participants (number of studies) Quality of evidence Total mortality 68 per 1,000 72 per 1,000 NA* 9,484 (6) Moderate Serious adverse effects 252 per 1,000 255 per 1,000 NA* 9,484 (6) Low Total CV events 127 per 1,000 113 per 1,000 NA* 9,484 (6) Low CV mortality 31 per 1,000 32 per 1,000 NA* 9,484 (6) Moderate Withdrawals because of adverse effects 7 per 1,000 60 per 1,000 19 (4 to 111) 690 (2) Very low BP= blood pressure; CI= confidence interval; CV= cardiovascular; NA= not applicable; NNH= number needed to harm; NNT= number needed to treat.*-No statistical difference in outcomes. Of those patients with hypertension, only 75 …

M3 - Review article

SN - 0002-838X

VL - 98

SP - 276

JO - American Family Physician

JF - American Family Physician

IS - 5

ER -

Blood Pressure Targets for Patients with Hypertension and Cardiovascular Disease

Abstract

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