Bone marrow-derived lymphoid cells (B cells): Functional depletion with cobra factor and fresh serum

Nelson L. Levy; David W. Scott; Ralph Snyderman

doi:10.1126/science.178.4063.866

Bone marrow-derived lymphoid cells (B cells): Functional depletion with cobra factor and fresh serum

Nelson L. Levy^*, David W. Scott, Ralph Snyderman

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Treatment of rat spleen cells with cobra factor and fresh rat serum provided a simple, rapid means of functionally eliminating complement receptor lymphocytes. Cells able to differentiate into plaque-forming cells in a syngeneic, irradiated host were diminished, but cells able to induce a graft-versus-host reaction were not diminished. There was no effect on plaque-forming cells from an immune spleen.

Original language	English
Pages (from-to)	866-867
Number of pages	2
Journal	Science
Volume	178
Issue number	4063
DOIs	https://doi.org/10.1126/science.178.4063.866
State	Published - 1972
Externally published	Yes

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title = "Bone marrow-derived lymphoid cells (B cells): Functional depletion with cobra factor and fresh serum",

abstract = "Treatment of rat spleen cells with cobra factor and fresh rat serum provided a simple, rapid means of functionally eliminating complement receptor lymphocytes. Cells able to differentiate into plaque-forming cells in a syngeneic, irradiated host were diminished, but cells able to induce a graft-versus-host reaction were not diminished. There was no effect on plaque-forming cells from an immune spleen.",

author = "Levy, {Nelson L.} and Scott, {David W.} and Ralph Snyderman",

year = "1972",

doi = "10.1126/science.178.4063.866",

language = "English",

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pages = "866--867",

journal = "Science",

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TY - JOUR

T1 - Bone marrow-derived lymphoid cells (B cells)

T2 - Functional depletion with cobra factor and fresh serum

AU - Levy, Nelson L.

AU - Scott, David W.

AU - Snyderman, Ralph

PY - 1972

Y1 - 1972

N2 - Treatment of rat spleen cells with cobra factor and fresh rat serum provided a simple, rapid means of functionally eliminating complement receptor lymphocytes. Cells able to differentiate into plaque-forming cells in a syngeneic, irradiated host were diminished, but cells able to induce a graft-versus-host reaction were not diminished. There was no effect on plaque-forming cells from an immune spleen.

AB - Treatment of rat spleen cells with cobra factor and fresh rat serum provided a simple, rapid means of functionally eliminating complement receptor lymphocytes. Cells able to differentiate into plaque-forming cells in a syngeneic, irradiated host were diminished, but cells able to induce a graft-versus-host reaction were not diminished. There was no effect on plaque-forming cells from an immune spleen.

UR - http://www.scopus.com/inward/record.url?scp=0015522248&partnerID=8YFLogxK

U2 - 10.1126/science.178.4063.866

DO - 10.1126/science.178.4063.866

M3 - Article

C2 - 4404438

AN - SCOPUS:0015522248

SN - 0036-8075

VL - 178

SP - 866

EP - 867

JO - Science

JF - Science

IS - 4063

ER -

Bone marrow-derived lymphoid cells (B cells): Functional depletion with cobra factor and fresh serum

Abstract

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