Brief Report: Association of Complicated Appendicitis in Children with Autism Spectrum Disorders

Patrick T. Reeves; Apryl Susi; Elizabeth Hisle-Gorman; Gregory H. Gorman; Cade Nylund

doi:10.1007/s10803-020-04499-z

Brief Report: Association of Complicated Appendicitis in Children with Autism Spectrum Disorders

Patrick T. Reeves^*, Apryl Susi, Elizabeth Hisle-Gorman, Gregory H. Gorman, Cade Nylund

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Appendicitis is the most common surgical emergency in children and can lead to significant complications. The aim of our study was to determine whether children with autism spectrum disorders (ASD) are at increased risk for appendicitis and its complications compared to neurotypical (NT) peers. From 2000 to 2013, 292,572 children were included (n = 48,762 ASD). ASD children exhibited an incidence of 8.66 appendicitis cases per 10,000 person-years, P > 0.05. There was an increased risk of perforation in ASD children age 15–17 years-old (OR 2.25; 95% CI 1.15–4.42) as well as an increased odds of sepsis (OR 3.44, 95% CI 1.43–8.27). Providers should display heightened awareness for the risk of complicated appendicitis in children with ASD.

Original language	English
Pages (from-to)	4535-4540
Number of pages	6
Journal	Journal of autism and developmental disorders
Volume	50
Issue number	12
DOIs	https://doi.org/10.1007/s10803-020-04499-z
State	Published - Dec 2020

Keywords

Appendicitis
Autism spectrum disorders
Perforation
Peritonitis
Sepsis

Access to Document

10.1007/s10803-020-04499-z

Cite this

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title = "Brief Report: Association of Complicated Appendicitis in Children with Autism Spectrum Disorders",

abstract = "Appendicitis is the most common surgical emergency in children and can lead to significant complications. The aim of our study was to determine whether children with autism spectrum disorders (ASD) are at increased risk for appendicitis and its complications compared to neurotypical (NT) peers. From 2000 to 2013, 292,572 children were included (n = 48,762 ASD). ASD children exhibited an incidence of 8.66 appendicitis cases per 10,000 person-years, P > 0.05. There was an increased risk of perforation in ASD children age 15–17 years-old (OR 2.25; 95% CI 1.15–4.42) as well as an increased odds of sepsis (OR 3.44, 95% CI 1.43–8.27). Providers should display heightened awareness for the risk of complicated appendicitis in children with ASD.",

keywords = "Appendicitis, Autism spectrum disorders, Perforation, Peritonitis, Sepsis",

author = "Reeves, {Patrick T.} and Apryl Susi and Elizabeth Hisle-Gorman and Gorman, {Gregory H.} and Cade Nylund",

note = "Publisher Copyright: {\textcopyright} 2020, This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.",

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AU - Nylund, Cade

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