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Case Report of an Urgent Determination of Malignant Hyperthermia Status of a 24-Week Pregnant Patient Requiring Intrauterine Fetal Surgery

  • Maria D Tischer
  • , David J Berman
  • , Luke Michaelson
  • , Erin A Tracy
  • , Rachel E Bridwell
  • , Angela M Curell

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Malignant hyperthermia (MH) is a potentially fatal disorder triggered by volatile anesthetics or succinylcholine, inducing a hypermetabolic crisis in susceptible patients. The caffeine-halothane contracture test (CHCT) remains a gold standard for MH detection. The authors describe a pregnant patient with a history of exertional rhabdomyolysis, who required urgent MH screening for administration of MH-triggering anesthetics. This anesthetic plan allowed for an in utero myelomeningocele repair for a 24-week-old fetus. A multi-institutional team coordinated the urgent CHCT and repair with a favorable outcome.

Original languageEnglish
Pages (from-to)e01868
JournalA&A practice
Volume18
Issue number12
DOIs
StatePublished - 1 Dec 2024

Keywords

  • Humans
  • Female
  • Pregnancy
  • Malignant Hyperthermia/diagnosis
  • Adult
  • Caffeine/administration & dosage
  • Halothane
  • Rhabdomyolysis
  • Meningomyelocele/surgery
  • Anesthetics, Inhalation/administration & dosage

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