@article{ab209b0642f2436eb211ca1014533138,
title = "Cellular Plasticity in Musculoskeletal Development, Regeneration, and Disease",
abstract = "In this review, we highlight themes from a recent workshop focused on “Plasticity of Cell Fate in Musculoskeletal Tissues” held at the Orthopaedic Research Society's 2019 annual meeting. Experts in the field provided examples of mesenchymal cell plasticity during normal musculoskeletal development, regeneration, and disease. A thorough understanding of the biology underpinning mesenchymal cell plasticity may offer a roadmap for promoting regeneration while attenuating pathologic differentiation.",
keywords = "heterotopic ossification, mesenchymal plasticity, musculoskeletal development, regeneration, transdifferentiation",
author = "Kaji, {Deepak A.} and Zhijia Tan and Johnson, {Gemma L.} and Wesley Huang and Kaetlin Vasquez and Lehoczky, {Jessica A.} and Benjamin Levi and Cheah, {Kathryn S.E.} and Huang, {Alice H.}",
note = "Funding Information: Grant sponsor: NIH; Grant number: R01AR069537; Grant sponsor: NYSTEM IDEA; Grant number: C32570GG; Grant sponsor: NIH; Grant number: 1R01AR071379; Grant sponsor: NIH; Grant number: F31AR073626; Grant sponsor: NIH; Grant numbers: R03HD093922 and R21HD097405; Grant sponsor: Research Grants Council of Hong Kong; Grant numbers: AoE/M‐04/04, T12‐708/12 N, GRF 17129017. Funding Information: Supported by funding from NIH R01AR069537 and NYSTEM IDEA grant (C32570GG) to A.H., NIH 1R01AR071379 to B.L., and NIH F31AR073626 to D.K. J.L. is funded by NIH R03HD093922, NIH R21HD097405, The Osher Center for Integrative Medicine, and funds from BWH Department of Orthopedic Surgery. This work was also supported by the Research Grants Council of Hong Kong AoE/M‐04/04, T12‐708/12N, GRF 17129017 to K.C. We also acknowledge Jill Gregory at Mount Sinai for assistance with the epigenetic “subway” map graphic. Publisher Copyright: {\textcopyright} 2019 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.",
year = "2020",
month = apr,
day = "1",
doi = "10.1002/jor.24523",
language = "English",
volume = "38",
pages = "708--718",
journal = "Journal of Orthopaedic Research",
issn = "0736-0266",
number = "4",
}