Chemotherapy, Biologic, and Immunotherapy Breakthroughs in Cancer Care

Christine Rojas, Yovanni Casablanca*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


As the understanding of cancer biology expands, a wider array of treatment options has become available in the field of gynecologic cancer. Therapies that target specific molecular pathways are now being used. Drugs that target cancer angiogenesis, signal transduction, DNA repair, and immune evasion mechanisms are currently being used, in addition to or in lieu of traditional chemotherapy, to achieve more personalized treatment of each patient and their unique disease. These therapies may lead to improved survival outcomes and quality of life during treatment and during remission.

Original languageEnglish
Pages (from-to)137-154
Number of pages18
JournalObstetrics and Gynecology Clinics of North America
Issue number1
StatePublished - Mar 2019
Externally publishedYes


  • Antiangiogenic therapy
  • Chemotherapy
  • Immunotherapy
  • PARP inhibitors
  • Targeted therapy
  • Toxicity
  • Tyrosine kinase inhibitors (TKI)


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