Circadian Variation in Myocardial Infarction

Merrill M. Mitler, Daniel F. Kripke, L. E.M. Schwab, Harry B. Burke, James E. Muller

Research output: Contribution to journalLetterpeer-review

17 Scopus citations


To the Editor: The morning peak in incidence of myocardial infarction described by Muller et al. (November 21 issue)1 is consistent with a number of studies on the circadian distribution of human mortality.2 3 4 5 6 Mitler et al. reported on 4920 disease-related deaths randomly sampled from death certificates at the New York City Bureau of Vital Statistics for 1979.6 There were 2463 deaths in that sample that were recorded as being due to ischemic heart disease (International Classification of Diseases, ninth revision [Clinical Modification], codes 410 to 414). Like the myocardial infarctions described by Muller et al., deaths…

Original languageEnglish
Pages (from-to)1187-1189
Number of pages3
JournalNew England Journal of Medicine
Issue number18
StatePublished - 1 May 1986
Externally publishedYes


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