Clinical experimentation with aerosol antibiotics: Current and future methods of administration

Paul Zarogoulidis; Ioannis Kioumis; Konstantinos Porpodis; Dionysios Spyratos; Kosmas Tsakiridis; Haidong Huang; Qiang Li; J. Francis Turner; Robert Browning; Wolfgang Hohenforst-Schmidt; Konstantinos Zarogoulidis

doi:10.2147/DDDT.S51303

Clinical experimentation with aerosol antibiotics: Current and future methods of administration

Paul Zarogoulidis^*, Ioannis Kioumis, Konstantinos Porpodis, Dionysios Spyratos, Kosmas Tsakiridis, Haidong Huang, Qiang Li, J. Francis Turner, Robert Browning, Wolfgang Hohenforst-Schmidt, Konstantinos Zarogoulidis

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

33 Scopus citations

Abstract

Currently almost all antibiotics are administered by the intravenous route. Since several systems and situations require more efficient methods of administration, investigation and experimentation in drug design has produced local treatment modalities. Administration of antibiotics in aerosol form is one of the treatment methods of increasing interest. As the field of drug nanotechnology grows, new molecules have been produced and combined with aerosol production systems. In the current review, we discuss the efficiency of aerosol antibiotic studies along with aerosol production systems. The different parts of the aerosol antibiotic methodology are presented. Additionally, information regarding the drug molecules used is presented and future applications of this method are discussed.

Original language	English
Pages (from-to)	1115-1134
Number of pages	20
Journal	Drug Design, Development and Therapy
Volume	7
DOIs	https://doi.org/10.2147/DDDT.S51303
State	Published - 1 Oct 2013
Externally published	Yes

Keywords

Aerosol
Antibiotics
Nebulizers

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abstract = "Currently almost all antibiotics are administered by the intravenous route. Since several systems and situations require more efficient methods of administration, investigation and experimentation in drug design has produced local treatment modalities. Administration of antibiotics in aerosol form is one of the treatment methods of increasing interest. As the field of drug nanotechnology grows, new molecules have been produced and combined with aerosol production systems. In the current review, we discuss the efficiency of aerosol antibiotic studies along with aerosol production systems. The different parts of the aerosol antibiotic methodology are presented. Additionally, information regarding the drug molecules used is presented and future applications of this method are discussed.",

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AU - Zarogoulidis, Paul

AU - Kioumis, Ioannis

AU - Porpodis, Konstantinos

AU - Spyratos, Dionysios

AU - Tsakiridis, Kosmas

AU - Huang, Haidong

AU - Li, Qiang

AU - Turner, J. Francis

AU - Browning, Robert

AU - Hohenforst-Schmidt, Wolfgang

AU - Zarogoulidis, Konstantinos

PY - 2013/10/1

Y1 - 2013/10/1

N2 - Currently almost all antibiotics are administered by the intravenous route. Since several systems and situations require more efficient methods of administration, investigation and experimentation in drug design has produced local treatment modalities. Administration of antibiotics in aerosol form is one of the treatment methods of increasing interest. As the field of drug nanotechnology grows, new molecules have been produced and combined with aerosol production systems. In the current review, we discuss the efficiency of aerosol antibiotic studies along with aerosol production systems. The different parts of the aerosol antibiotic methodology are presented. Additionally, information regarding the drug molecules used is presented and future applications of this method are discussed.

AB - Currently almost all antibiotics are administered by the intravenous route. Since several systems and situations require more efficient methods of administration, investigation and experimentation in drug design has produced local treatment modalities. Administration of antibiotics in aerosol form is one of the treatment methods of increasing interest. As the field of drug nanotechnology grows, new molecules have been produced and combined with aerosol production systems. In the current review, we discuss the efficiency of aerosol antibiotic studies along with aerosol production systems. The different parts of the aerosol antibiotic methodology are presented. Additionally, information regarding the drug molecules used is presented and future applications of this method are discussed.

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KW - Nebulizers

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Clinical experimentation with aerosol antibiotics: Current and future methods of administration

Abstract

Keywords

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