Clustering Big Cancer Data by Effect Sizes

Huan Wang, Dechang Chen, Matthew T. Hueman, Li Sheng, Donald E. Henson

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

11 Scopus citations

Abstract

We propose an effect size based approach to compute initial dissimilarities for Ensemble Algorithm of Clustering Cancer Data (EACCD). The proposed method is applied to the colon cancer data from the Surveillance, Epidemiology, and End Results (SEER) Program of the National Cancer Institute and compared with the log-rank approach where initial dissimilarities are computed from the log-rank test statistic. The experimental results show that under the proportional hazards assumption, the effect size approach generates robust results and has a better performance than the log-rank approach.

Original languageEnglish
Title of host publicationProceedings - 2017 IEEE 2nd International Conference on Connected Health
Subtitle of host publicationApplications, Systems and Engineering Technologies, CHASE 2017
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages58-63
Number of pages6
ISBN (Electronic)9781509047215
DOIs
StatePublished - 14 Aug 2017
Externally publishedYes
Event2nd IEEE International Conference on Connected Health: Applications, Systems and Engineering Technologies, CHASE 2017 - Philadelphia, United States
Duration: 17 Jul 201719 Jul 2017

Publication series

NameProceedings - 2017 IEEE 2nd International Conference on Connected Health: Applications, Systems and Engineering Technologies, CHASE 2017

Conference

Conference2nd IEEE International Conference on Connected Health: Applications, Systems and Engineering Technologies, CHASE 2017
Country/TerritoryUnited States
CityPhiladelphia
Period17/07/1719/07/17

Keywords

  • TNM
  • colon cancer
  • dendrogram
  • hierarchical clustering
  • prognostic system
  • survival

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