Clustering Cancer Data by Areas between Survival Curves

Dechang Chen, Huan Wang, Donald E. Henson, Li Sheng, Matthew T. Hueman, Arnold M. Schwartz

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

3 Scopus citations

Abstract

We propose a hierarchical clustering method for prognostic clustering of cancer patients. Dissimilarity between two subsets of patients is defined as the area between two corresponding Kaplan-Meier curves. The proposed method is applied to the breast cancer data from the Surveillance, Epidemiology, and End Results (SEER) Program of the National Cancer Institute and compared with the linkage approach. The proposed method is convenient to use and can generate dendrograms compatible with those from the linkage approach.

Original languageEnglish
Title of host publicationProceedings - 2016 IEEE 1st International Conference on Connected Health
Subtitle of host publicationApplications, Systems and Engineering Technologies, CHASE 2016
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages61-66
Number of pages6
ISBN (Electronic)9781509009435
DOIs
StatePublished - 16 Aug 2016
Externally publishedYes
Event1st IEEE International Conference on Connected Health: Applications, Systems and Engineering Technologies, CHASE 2016 - Washington, United States
Duration: 27 Jun 201629 Jun 2016

Publication series

NameProceedings - 2016 IEEE 1st International Conference on Connected Health: Applications, Systems and Engineering Technologies, CHASE 2016

Conference

Conference1st IEEE International Conference on Connected Health: Applications, Systems and Engineering Technologies, CHASE 2016
Country/TerritoryUnited States
CityWashington
Period27/06/1629/06/16

Keywords

  • TNM
  • area between curves
  • breast cancer
  • dendrogram
  • hierarchical clustering
  • prognostic system
  • survival

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