TY - JOUR
T1 - Coagulation During Hypothermia in Man
AU - Bunker, John P.
AU - Goldstein, Robert
PY - 1958/1
Y1 - 1958/1
N2 - Clotting times, platelets, thromboplastin generation, prothrombin consumption, prothrombin time, and concentrations of prothrombin, accelerator globulin, proconvertin, and fibrinogen were measured in 10 patients after the slow induction of hypothermia and later during surgery and transfusion. In contrast to previous studies in the dog, uncomplicated hypothermia in man was not associated with a fall in concentration of clotting factors. Moderate disturbances in coagulation with surgery and transfusion during hypothermia were in most regards similar to those observed during surgery and transfusion at normal body temperature. The one significant difference was a decrease in prothrombin consumption.
AB - Clotting times, platelets, thromboplastin generation, prothrombin consumption, prothrombin time, and concentrations of prothrombin, accelerator globulin, proconvertin, and fibrinogen were measured in 10 patients after the slow induction of hypothermia and later during surgery and transfusion. In contrast to previous studies in the dog, uncomplicated hypothermia in man was not associated with a fall in concentration of clotting factors. Moderate disturbances in coagulation with surgery and transfusion during hypothermia were in most regards similar to those observed during surgery and transfusion at normal body temperature. The one significant difference was a decrease in prothrombin consumption.
UR - http://www.scopus.com/inward/record.url?scp=0004391258&partnerID=8YFLogxK
U2 - 10.3181/00379727-97-23689
DO - 10.3181/00379727-97-23689
M3 - Article
C2 - 13518222
AN - SCOPUS:0004391258
SN - 0037-9727
VL - 97
SP - 199
EP - 202
JO - Proceedings of the Society for Experimental Biology and Medicine
JF - Proceedings of the Society for Experimental Biology and Medicine
IS - 1
ER -