Colistin heteroresistance in Acinetobacter and its association with previous colistin therapy

Joshua S. Hawley; Clinton K. Murray; James H. Jorgensen

doi:10.1128/AAC.00766-07

Colistin heteroresistance in Acinetobacter and its association with previous colistin therapy

Joshua S. Hawley, Clinton K. Murray^*, James H. Jorgensen

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

170 Scopus citations

Abstract

Colistin heteroresistance has been reported among Acinetobacter isolates; however, its association with prior colistin therapy has not been not described. A population analysis profile identified resistant Acinetobacter subpopulations from colistin-susceptible clinical isolates. The proportion of cells exhibiting heteroresistance was significantly higher among isolates recovered from patients treated with colistin.

Original language	English
Pages (from-to)	351-352
Number of pages	2
Journal	Antimicrobial Agents and Chemotherapy
Volume	52
Issue number	1
DOIs	https://doi.org/10.1128/AAC.00766-07
State	Published - Jan 2008
Externally published	Yes

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title = "Colistin heteroresistance in Acinetobacter and its association with previous colistin therapy",

abstract = "Colistin heteroresistance has been reported among Acinetobacter isolates; however, its association with prior colistin therapy has not been not described. A population analysis profile identified resistant Acinetobacter subpopulations from colistin-susceptible clinical isolates. The proportion of cells exhibiting heteroresistance was significantly higher among isolates recovered from patients treated with colistin.",

author = "Hawley, {Joshua S.} and Murray, {Clinton K.} and Jorgensen, {James H.}",

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AU - Hawley, Joshua S.

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N2 - Colistin heteroresistance has been reported among Acinetobacter isolates; however, its association with prior colistin therapy has not been not described. A population analysis profile identified resistant Acinetobacter subpopulations from colistin-susceptible clinical isolates. The proportion of cells exhibiting heteroresistance was significantly higher among isolates recovered from patients treated with colistin.

AB - Colistin heteroresistance has been reported among Acinetobacter isolates; however, its association with prior colistin therapy has not been not described. A population analysis profile identified resistant Acinetobacter subpopulations from colistin-susceptible clinical isolates. The proportion of cells exhibiting heteroresistance was significantly higher among isolates recovered from patients treated with colistin.

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JF - Antimicrobial Agents and Chemotherapy

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Colistin heteroresistance in Acinetobacter and its association with previous colistin therapy

Abstract

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