Colonoscopy for Colorectal Cancer Screening: Current Challenges and Future Directions

Amilcar L. Morales, John P. Magulick, Craig Womeldorph, Patrick E. Young*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


It is estimated that over 50,000 people will die from colorectal cancer (CRC) in 2014, making CRC the third leading cause of cancer death in the USA. During the last decade, we gained a better understanding of CRC pathophysiology and improved techniques for CRC prevention. Colonoscopy, as a cancer prevention measure, is essential in this task. Our article will review several aspects of colonoscopy and its use in CRC prevention. In addition, we will cover non-technical aspect such as quality measures, improving colonoscopy uptake, new bowel preparation formulations, sedation, and quality metrics. Next, we will discuss advances in technology and techniques including water immersion, new colonoscopes, and new imaging methods. Finally, we will cover two areas of major recent interest, “resect and discard” and sessile serrated polyps.

Original languageEnglish
JournalCurrent Colorectal Cancer Reports
Issue number1
StatePublished - Feb 2014
Externally publishedYes


  • Bowel preparation
  • Cap-assisted colonoscopy
  • Colonoscopy
  • Colonoscopy uptake
  • Colorectal cancer
  • Enhanced imaging technology
  • Quality metrics
  • Resect and discard
  • Screening
  • Sessile serrated polyps


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