Colorectal Cancer Screening: a North American Point of View

Induruwa N. Pathirana*, Dustin M. Albert, Patrick E. Young, Craig M. Womeldorph

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


Worldwide, colorectal cancer (CRC) is the third most commonly diagnosed cancer in males and second in females, with an estimated 1.4 million cases and 693,900 deaths in 2012. The current screening modalities utilized in the USA are examined in this review, along with current colonoscopy quality indicators. The contribution of CRC screening to the rising cost of health care in the USA has warranted recent public interest and has overall been demonstrated to be cost-effective. In addition, numerous barriers to screening are analyzed along with models for risk stratifying CRC risk at both an individual and population level. Recently, recognized risk stratification models from the Netherlands and Asia are compared with those developed in the USA, and the applicability of each to the US population is evaluated. Ultimately, this review presents the challenges and potential solutions in moving forward in the realm of CRC screening.

Original languageEnglish
Pages (from-to)241-250
Number of pages10
JournalCurrent Colorectal Cancer Reports
Issue number5
StatePublished - 1 Oct 2016
Externally publishedYes


  • Cancer screening
  • Colonic neoplasms
  • Colonoscopy
  • Colorectal cancer
  • Polyps
  • Public health


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