TY - JOUR
T1 - Comparison of clinical presentation of acute myocarditis following smallpox vaccination to acute coronary syndromes in patients <40 years of age
AU - Eckart, Robert E.
AU - Shry, Eric A.
AU - Jones IV, Samuel O.
AU - Atwood, J. Edwin
AU - Grabenstein, John D.
PY - 2005/5/15
Y1 - 2005/5/15
N2 - Smallpox vaccine-associated myopericarditis may have a similar presentation to acute coronary syndrome (ACS). The clinical records of 78 young patients (<40 years of age) presenting with ACS (n = 16) or myocarditis after smallpox vaccination (n = 62) were reviewed. Comparisons were made among clinical presentation, cardiac enzymes, echocardiographic findings, and electrocardiographic changes. The presence of cardiac risk factors or focal wall motion abnormalities on echocardiography were associated with a diagnosis of ACS. There was a trend toward earlier elevation of troponin-I and creatine kinase in patients with myocarditis compared with ACS.
AB - Smallpox vaccine-associated myopericarditis may have a similar presentation to acute coronary syndrome (ACS). The clinical records of 78 young patients (<40 years of age) presenting with ACS (n = 16) or myocarditis after smallpox vaccination (n = 62) were reviewed. Comparisons were made among clinical presentation, cardiac enzymes, echocardiographic findings, and electrocardiographic changes. The presence of cardiac risk factors or focal wall motion abnormalities on echocardiography were associated with a diagnosis of ACS. There was a trend toward earlier elevation of troponin-I and creatine kinase in patients with myocarditis compared with ACS.
UR - http://www.scopus.com/inward/record.url?scp=18144382253&partnerID=8YFLogxK
U2 - 10.1016/j.amjcard.2005.01.061
DO - 10.1016/j.amjcard.2005.01.061
M3 - Article
C2 - 15878006
AN - SCOPUS:18144382253
SN - 0002-9149
VL - 95
SP - 1252
EP - 1255
JO - The American Journal of Cardiology
JF - The American Journal of Cardiology
IS - 10
ER -