TY - JOUR
T1 - Comparison of the urine leukocyte esterase test to a nucleic acid amplification test for screening non-health care-seeking male soldiers for Chlamydia trachomatis and Neisseria gonorrhoeae infections
AU - Wood, Billie Jo
AU - Gaydos, Joel C.
AU - McKee, Kelly T.
AU - Gaydos, Charlotte A.
PY - 2007/7
Y1 - 2007/7
N2 - We evaluated the Leukocyte Esterase Test (LET) as a screening tool by testing urine from 1,438 non-health care-seeking male Army basic trainees with LET and a Nucleic Acid Amplification Test. Compared to Nucleic Acid Amplification Test results, LET sensitivity and specificity for detection of chlamydia and gonorrhea were 45.8% and 97.4%, and 60.0% and 96.2%, respectively. The prevalence of chlamydia and gonorrhea was 3.3% and 0.3%, respectively. In this population, the prevalence of gonorrhea was too low to produce reliable estimates of performance characteristics of the LET for gonorrhea. The LET is not warranted for use in screening non-health care-seeking male Army trainees.
AB - We evaluated the Leukocyte Esterase Test (LET) as a screening tool by testing urine from 1,438 non-health care-seeking male Army basic trainees with LET and a Nucleic Acid Amplification Test. Compared to Nucleic Acid Amplification Test results, LET sensitivity and specificity for detection of chlamydia and gonorrhea were 45.8% and 97.4%, and 60.0% and 96.2%, respectively. The prevalence of chlamydia and gonorrhea was 3.3% and 0.3%, respectively. In this population, the prevalence of gonorrhea was too low to produce reliable estimates of performance characteristics of the LET for gonorrhea. The LET is not warranted for use in screening non-health care-seeking male Army trainees.
UR - http://www.scopus.com/inward/record.url?scp=34447517259&partnerID=8YFLogxK
U2 - 10.7205/MILMED.172.7.770
DO - 10.7205/MILMED.172.7.770
M3 - Article
C2 - 17691693
AN - SCOPUS:34447517259
SN - 0026-4075
VL - 172
SP - 770
EP - 772
JO - Military Medicine
JF - Military Medicine
IS - 7
ER -