Complete nucleotide sequence analysis of a Western Pacific dengue-1 virus strain

Beena Puri; William Nelson; Kevin R. Porter; Erik A. Henchal; Curtis G. Hayes

doi:10.1023/A:1008009202695

Complete nucleotide sequence analysis of a Western Pacific dengue-1 virus strain

Beena Puri^*, William Nelson, Kevin R. Porter, Erik A. Henchal, Curtis G. Hayes

^*Corresponding author for this work

Medicine

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

We have determined the complete nucleotide sequence and the deduced amino acid polypeptide sequence of the genome of a dengue-1 (DEN-1) virus strain isolated from a patient on Nauru in the Western Pacific in 1974 (West Pac 74). The complete genome is 10,735 nucleotides in length and contains a single long open reading frame of 10,176 nucleotides encoding a polyprotein of 3392 amino acids. When compared to DEN-1 Singapore S275/90, the nucleotide and amino acid sequence homology are 94% and 97.8%, respectively.

Original language	English
Pages (from-to)	85-88
Number of pages	4
Journal	Virus Genes
Volume	17
Issue number	1
DOIs	https://doi.org/10.1023/A:1008009202695
State	Published - 1998

Keywords

Dengue-1 western pacific virus
Flavivirus
Nucleotide sequence

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10.1023/A:1008009202695

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abstract = "We have determined the complete nucleotide sequence and the deduced amino acid polypeptide sequence of the genome of a dengue-1 (DEN-1) virus strain isolated from a patient on Nauru in the Western Pacific in 1974 (West Pac 74). The complete genome is 10,735 nucleotides in length and contains a single long open reading frame of 10,176 nucleotides encoding a polyprotein of 3392 amino acids. When compared to DEN-1 Singapore S275/90, the nucleotide and amino acid sequence homology are 94% and 97.8%, respectively.",

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AU - Nelson, William

AU - Porter, Kevin R.

AU - Henchal, Erik A.

AU - Hayes, Curtis G.

PY - 1998

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AB - We have determined the complete nucleotide sequence and the deduced amino acid polypeptide sequence of the genome of a dengue-1 (DEN-1) virus strain isolated from a patient on Nauru in the Western Pacific in 1974 (West Pac 74). The complete genome is 10,735 nucleotides in length and contains a single long open reading frame of 10,176 nucleotides encoding a polyprotein of 3392 amino acids. When compared to DEN-1 Singapore S275/90, the nucleotide and amino acid sequence homology are 94% and 97.8%, respectively.

KW - Dengue-1 western pacific virus

KW - Flavivirus

KW - Nucleotide sequence

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JO - Virus Genes

JF - Virus Genes

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Complete nucleotide sequence analysis of a Western Pacific dengue-1 virus strain

Abstract

Keywords

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