Concurrent Validity of Q-TFA With PROMIS and Prosthetic Wear Time in Transfemoral Amputees

Samir Sabharwal*, Richard L. Skolasky, Jason M. Souza, Benjamin K. Potter, Jonathan A. Forsberg

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Objectives:To evaluate whether the Questionnaire for Persons with a Transfemoral Amputation (Q-TFA) significantly correlates with select Patient-Reported Outcomes Measurement Information System (PROMIS) domains and self-reported prosthetic wear time in transfemoral amputees presenting for consideration of osseointegration.Design:This was a prospective study.Setting:Osseointegration Clinic, Walter Reed National Medical Center, Bethesda, MD.Participants:Patients who presented between 2017 and 2020 for consideration of osseointegration after transfemoral amputation.Intervention:We prospectively administered Q-TFA (including use, mobility, problems, and global health subscores) and PROMIS (including physical function, pain interference, and pain behavior domains) questionnaires. We also asked participants to self-report prosthetic wear time.Main Outcome Measurement:The main outcome measurement was concurrent validity, which was assessed through the Pearson correlation testing.Results:Among our 39 patients, the Pearson testing demonstrated significant correlation between the following: Q-TFA use and self-reported prosthetic wear time (r = 0.81, P < 0.001); Q-TFA mobility and PROMIS physical function (r = 0.44, P = 0.009); Q-TFA problems and PROMIS pain interference (r = 0.60, P < 0.001); and Q-TFA global health and PROMIS physical function (r = 0.35, P = 0.04).Conclusions:Across all 4 domains of Q-TFA, correlation testing established significant concurrent validity with select PROMIS domains and self-reported prosthetic wear time among our population of transfemoral amputees. Given its ease of administration and reduction of question burden, PROMIS may better serve our efforts to track the outcomes of future interventions - including osseointegration - for these patients.

Original languageEnglish
Pages (from-to)361-365
Number of pages5
JournalJournal of Orthopaedic Trauma
Issue number7
StatePublished - 1 Jul 2022
Externally publishedYes


  • Q-TFA
  • patient-reported outcomes measures
  • transfemoral amputation


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