Continuous light paradoxically reduces catecholamine-induced melatonin production

William E. Heydorn; Irwin Lucki; Alan Frazer

doi:10.1016/0006-8993(83)91054-5

Continuous light paradoxically reduces catecholamine-induced melatonin production

William E. Heydorn, Irwin Lucki, Alan Frazer^*

^*Corresponding author for this work

Pharmacology and Molecular Therapeutics

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Exposure of rats to continuous light for 14 days reduced the stimulation of melatonin content in the pineal gland produced by either isoproterenol administration or exposure to darkness. Since continuous light has been reported to enhance many intermediate biochemical events leading to the synthesis of melatonin, these results demonstrate the importance of examining the end-product of an organ when evaluating the physiological significance of biochemical changes in model biological systems.

Original language	English
Pages (from-to)	175-178
Number of pages	4
Journal	Brain Research
Volume	267
Issue number	1
DOIs	https://doi.org/10.1016/0006-8993(83)91054-5
State	Published - 9 May 1983

Keywords

beta-receptors
continuous light
isoproterenol
norepinephrine
pineal gland

Access to Document

10.1016/0006-8993(83)91054-5

Cite this

@article{5ab099a5aebc46119eaabfe26ac8d7bb,

title = "Continuous light paradoxically reduces catecholamine-induced melatonin production",

abstract = "Exposure of rats to continuous light for 14 days reduced the stimulation of melatonin content in the pineal gland produced by either isoproterenol administration or exposure to darkness. Since continuous light has been reported to enhance many intermediate biochemical events leading to the synthesis of melatonin, these results demonstrate the importance of examining the end-product of an organ when evaluating the physiological significance of biochemical changes in model biological systems.",

keywords = "beta-receptors, continuous light, isoproterenol, norepinephrine, pineal gland",

author = "Heydorn, \{William E.\} and Irwin Lucki and Alan Frazer",

year = "1983",

month = may,

day = "9",

doi = "10.1016/0006-8993(83)91054-5",

language = "English",

volume = "267",

pages = "175--178",

journal = "Brain Research",

issn = "0006-8993",

publisher = "Elsevier B.V.",

number = "1",

}

TY - JOUR

T1 - Continuous light paradoxically reduces catecholamine-induced melatonin production

AU - Heydorn, William E.

AU - Lucki, Irwin

AU - Frazer, Alan

PY - 1983/5/9

Y1 - 1983/5/9

N2 - Exposure of rats to continuous light for 14 days reduced the stimulation of melatonin content in the pineal gland produced by either isoproterenol administration or exposure to darkness. Since continuous light has been reported to enhance many intermediate biochemical events leading to the synthesis of melatonin, these results demonstrate the importance of examining the end-product of an organ when evaluating the physiological significance of biochemical changes in model biological systems.

AB - Exposure of rats to continuous light for 14 days reduced the stimulation of melatonin content in the pineal gland produced by either isoproterenol administration or exposure to darkness. Since continuous light has been reported to enhance many intermediate biochemical events leading to the synthesis of melatonin, these results demonstrate the importance of examining the end-product of an organ when evaluating the physiological significance of biochemical changes in model biological systems.

KW - beta-receptors

KW - continuous light

KW - isoproterenol

KW - norepinephrine

KW - pineal gland

UR - http://www.scopus.com/inward/record.url?scp=0020522352&partnerID=8YFLogxK

U2 - 10.1016/0006-8993(83)91054-5

DO - 10.1016/0006-8993(83)91054-5

M3 - Article

C2 - 6860943

AN - SCOPUS:0020522352

SN - 0006-8993

VL - 267

SP - 175

EP - 178

JO - Brain Research

JF - Brain Research

IS - 1

ER -

Continuous light paradoxically reduces catecholamine-induced melatonin production

Abstract

Keywords

Access to Document

Fingerprint

Cite this