Correlation of hydrophobicity and packing in a-dna oligonucleotides

M. Sundaralingam; R. Biswas

doi:10.1080/07391102.1997.10508184

Correlation of hydrophobicity and packing in a-dna oligonucleotides

M. Sundaralingam^*
, R. Biswas

^*Corresponding author for this work

Anatomy, Physiology, and Genetics

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

A-DNA oligomers pack in a slanted fashion with the terminal base pairs abutting into the minor groove of neighboring molecules unlike the other forms of DNA which pack by vertically stacking one over the other into helical columns. To explain the differences in packing we have advanced a hypothesis that the orientation of the sugar-phosphate backbone is different in A-DNA from that in the other forms of DNA, mainly due to the differences in the sugar puckering.

Original language	English
Pages (from-to)	173-176
Number of pages	4
Journal	Journal of Biomolecular Structure and Dynamics
Volume	15
Issue number	2
DOIs	https://doi.org/10.1080/07391102.1997.10508184
State	Published - Oct 1997

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10.1080/07391102.1997.10508184

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title = "Correlation of hydrophobicity and packing in a-dna oligonucleotides",

abstract = "A-DNA oligomers pack in a slanted fashion with the terminal base pairs abutting into the minor groove of neighboring molecules unlike the other forms of DNA which pack by vertically stacking one over the other into helical columns. To explain the differences in packing we have advanced a hypothesis that the orientation of the sugar-phosphate backbone is different in A-DNA from that in the other forms of DNA, mainly due to the differences in the sugar puckering.",

author = "M. Sundaralingam and R. Biswas",

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AU - Sundaralingam, M.

AU - Biswas, R.

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AB - A-DNA oligomers pack in a slanted fashion with the terminal base pairs abutting into the minor groove of neighboring molecules unlike the other forms of DNA which pack by vertically stacking one over the other into helical columns. To explain the differences in packing we have advanced a hypothesis that the orientation of the sugar-phosphate backbone is different in A-DNA from that in the other forms of DNA, mainly due to the differences in the sugar puckering.

UR - https://www.scopus.com/pages/publications/0030730069

U2 - 10.1080/07391102.1997.10508184

DO - 10.1080/07391102.1997.10508184

M3 - Article

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AN - SCOPUS:0030730069

SN - 0739-1102

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SP - 173

EP - 176

JO - Journal of Biomolecular Structure and Dynamics

JF - Journal of Biomolecular Structure and Dynamics

IS - 2

ER -

Correlation of hydrophobicity and packing in a-dna oligonucleotides

Abstract

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