COVID-19 Antibody Prevalence From July to September 2020 One Army Infantry Brigade’s Experience

Alex Y. Koo*, David K. Rodgers, Keaton A. Johnson, Leanna L. Gordon, Luke E. Mease, Kyle S. Couperus

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Objectives: Lab companies developed serology tests for antibody detection of severe acute respiratory syndrome corona-virus-2 (SARS-CoV-2) with United States Food and Drug Administration (FDA) emergency use authorization. Antibody detection uses purified proteins of SARS-CoV-2 to determine antibody binding via enzyme-linked immunosorbent assay, che-miluminescent immunoassay (CLIA), or colloidal gold-based immunochromatographic assay. With the advent of coronavi-rus disease 2019 (COVID-19), nucleic acid amplification technology (NAAT) SARS-CoV-2 testing for active infection was not widely available to healthy, active-duty Soldiers. The pur-pose of this surveillance survey was to determine the prevalence of prior SARS-CoV-2 infection and symptoms of COVID-19 within a mechanized infantry brigade. Materials and Methods: Active-duty military Servicemembers (≥ 18 years) from a mechanized infantry brigade provided serum samples for testing for the Elecsys® Anti-SARS-CoV-2 qualitative antibody test from June to September 2020 at Joint Base Lewis McChord (JBLM). In addition, participants filled out a questionnaire for symptoms and exposure to COVID-19 from January to September 2020. The surveillance team collected and analyzed antibody testing results and questionnaires from participants for antibody positivity rates and symptom prevalence. Results: A total of 264 participants were tested, with one (0.4%) participant testing positive for the SARS-CoV-2 antibody. On the question-naire, 144 of 264 (54.5%) endorsed symptoms of COVID-19 from January to September 2020. The most common symptoms were headache (35%), rhinorrhea (34%), cough (35%), and sore throat (31%). A total of 31 respondents (12%) had been quarantined as a trace contact to a COVID-19 positive patient. Conclusions: While there are limitations inherent to SARS-CoV-2 antibody testing and the survey, prevalence of prior SARS-CoV-2 infection is low. In this sample, symptoms for COVID-19 were prevalent with significant days of duty lost. Prevalence of prior SARS-CoV-2 infection in this sample may be generalizable to the larger brigade. Prevalence of symptoms of possible COVID-19 are not generalizable to the larger brigade. There is utility to further studies of SARS-CoV-2 antibody prevalence in military populations for purposes of vaccination triaging and deployment readiness.

Original languageEnglish
Pages (from-to)60-65
Number of pages6
JournalJournal of Special Operations Medicine
Issue number3
StatePublished - 1 Sep 2021
Externally publishedYes


  • Army Infantry Bri-gade
  • COVID-19
  • SARS-CoV-2
  • antibody
  • prevalence
  • vaccination
  • vaccine


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